Evidence map›Paper›PMID 35222014›Full record

ArticleFrontiers in pharmacology2021

A Mixture of Baicalein, Wogonin, and Oroxylin-A Inhibits EMT in the A549 Cell Line

Hui-Juan Cao, Wei Zhou, Xiao-Le Xian, Shu-Jun Sun, Pei-Jie Ding, Chun-Yu Tian, Fu-Ling Tian, Chun-Hua Jiang, Ting-Ting Fu, Shu Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  5. Bioactive Flavonoids fromDrug design, development and therapy · 2026
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  8. [Application ofZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Review
  9. Review
  10. Article
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  13. Article
  14. Roles of Twist1 in lipid and glucose metabolism.Cell communication and signaling : CCS · 2023
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Frontiers in genetics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Hui-Juan CaoTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Wei ZhouSchool of Pharmacy, Lanzhou University, Lanzhou, China.
Xiao-Le XianTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Shu-Jun SunSchool of Biology and Food Engineering, Fuyang Normal University, Fuyang, China.
Pei-Jie DingTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Chun-Yu TianTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Fu-Ling TianTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Chun-Hua JiangTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Ting-Ting FuTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Shu ZhaoTraditional Chinese Medicine College, North China University of Science and Technology, Tangshan, China.
Jian-Ye DaiSchool of Pharmacy, Lanzhou University, Lanzhou, China.
North China University of Science and Technology · CNLanzhou University · CNFuyang Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) is a worldwide disease with a high morbidity and mortality rate, which is most derived from its metastasis. Some studies show that the epithelial-mesenchymal transition (EMT) process promotes lung cancer cell migration and invasion, leading to NSCLC metastasis. Total flavonoid aglycones extract (TFAE) isolated from

Indexed as

epithelial–mesenchymal transitionPI3K/Akt signaling pathwayreconstructed TFAEstable isotope dimethyl-labeled proteomicsTwist1

Identifiers

PMID35222014
PMCPMC8864075
OpenAlexW4211243267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.