Evidence map›Paper›PMID 35221908›Full record

ArticleFrontiers in neuroscience2022

Experimental Exploration of Objective Human Pain Assessment Using Multimodal Sensing Signals.

Yingzi Lin, Yan Xiao, Li Wang, Yikang Guo, Wenchao Zhu, Biren Dalip, Sagar Kamarthi, Kristin L Schreiber, Robert R Edwards, Richard D Urman

Abstract read
In one paragraph

Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Continuous, Contactless, and Multimodal Pain Assessment During Surgical Interventions.IEEE open journal of engineering in medicine and biology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yingzi LinIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Yan XiaoCollege of Nursing and Health Innovation, University of Texas at Arlington, Arlington, TX, United States.
Li WangIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Yikang GuoIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Wenchao ZhuIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Biren DalipIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Sagar KamarthiIntelligent Human Machine Systems Laboratory, College of Engineering, Northeastern University, Boston, MA, United States.
Kristin L SchreiberDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard University, Boston, MA, United States.
Robert R EdwardsDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard University, Boston, MA, United States.
Richard D UrmanDepartment of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Harvard University, Boston, MA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimization of pain assessment and treatment is an active area of research in healthcare. The purpose of this research is to create an objective pain intensity estimation system based on multimodal sensing signals through experimental studies. Twenty eight healthy subjects were recruited at Northeastern University. Nine physiological modalities were utilized in this research, namely facial expressions (FE), electroencephalography (EEG), eye movement (EM), skin conductance (SC), and blood volume pulse (BVP), electromyography (EMG), respiration rate (RR), skin temperature (ST), blood pressure (BP). Statistical analysis and machine learning algorithms were deployed to analyze the physiological data. FE, EEG, SC, BVP, and BP proved to be able to detect different pain states from healthy subjects. Multi-modalities proved to be promising in detecting different levels of painful states. A decision-level multi-modal fusion also proved to be efficient and accurate in classifying painful states.

Indexed as

machine learning algorithmsmulti-modality sensor fusionpain measurementphysiological signalssensors

Identifiers

PMID35221908
PMCPMC8874020

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.