ArticleNeuropsychiatric disease and treatment2022
Relationship Between the Hemoglobin-to-Red Cell Distribution Width Ratio and All-Cause Mortality in Ischemic Stroke Patients with Atrial Fibrillation: An Analysis from the MIMIC-IV Database.
Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Association between lactate-to-albumin ratio and the short-time mortality of patients with ischemic stroke in intensive care unit.BMC neurology · 2026Article
- Article
- Predictive value of hemoglobin-to-red cell distribution width ratio for mortality in new-onset atrial fibrillation after cardiac surgery a machine learning study based on the MIMIC-IV database.BMC cardiovascular disorders · 2026Article
- Development and validation of predicting hospital mortality of acute ischemic stroke patients over 80 years in ICU: a retrospective study.BMC geriatrics · 2026Article
- Article
- The Predictive Value of Hemoglobin-to-Red Blood Cell Distribution Width Ratio for the Prognosis of Patients with Aortic Dissection: Based on the Medical Information Mart for Intensive Care-IV Database.Anatolian journal of cardiology · 2025Article
- Prognostic potential of albumin to fibrinogen ratio in multiple myeloma patients.Annals of hematology · 2025Article
- Association of Hemoglobin to Red Blood Cell Distribution Width Ratio and Total Bone Mineral Density in U.S. Adolescents: The NHANES 2011-2018.Diagnostics (Basel, Switzerland) · 2025Article
- The association between hemoglobin-to-red cell distribution width ratio and asthma and asthma exacerbations: a cross-sectional study.BMC pulmonary medicine · 2025Article
- Hematological parameters in atrial fibrillation: A literature review.World journal of cardiology · 2025Review
- Hemoglobin-to-Red Cell Distribution Width Ratio Was Associated with Cardiovascular Diseases and Death.Journal of clinical medicine · 2025Article
- Association of red cell distribution width/albumin ratio and 28-day mortality in chronic obstructive pulmonary disease patients with atrial fibrillation: a medical information mart for intensive care IV study.BMC cardiovascular disorders · 2025Article
- Identifying metabolic parameters as key indicators of hyperuricemia and ischemic stroke comorbidity via interpretable Clinlabomics models.Frontiers in endocrinology · 2025Article
- Association between the hemoglobin-to-red cell distribution width ratio and three-month unfavorable outcome in older acute ischemic stroke patients: a prospective study.Frontiers in neurology · 2025Article
- Relationship between the hemoglobin-to-red cell distribution width ratio and post-stroke cognitive impairment: a prospective study.Frontiers in aging neuroscience · 2025Article
- Association of hemoglobin-to-red cell distribution width ratio with diabetic retinopathy risk and severity.Frontiers in endocrinology · 2025Article
- Predictive Value of the Hb/RDW Ratio for the Risk of All-Cause Death in Patients with Heart Failure with Different Ejection Fractions.Cardiology · 2024Article
- Association of hemoglobin-to-red cell distribution width ratio with the three-month outcomes in patients with acute ischemic stroke.Frontiers in neurology · 2024Article
- Association of red blood cell distribution width to albumin ratio with prognosis in stroke patients.Biomarkers in medicine · 2024Article
- Association between baseline pulse pressure and hospital mortality in non-traumatic subarachnoid hemorrhage patients: a retrospective cohort study.Frontiers in neurology · 2023Article
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Authors and funding
6 authors.
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Abstract
aimTo investigate the association between the hemoglobin-to-red cell distribution width (RDW) ratio (HRR) and all-cause mortality in ischemic stroke patients with atrial fibrillation (AF).
designThis study was a retrospective cohort analysis. In total, 1018 ischemic stroke patients with AF were enrolled using the Medical Information Mart for Intensive Care database, (MIMIC)-IV. The patients were divided into four groups according to the HRR values. The primary outcome was 180-day all-cause mortality.
methodsMultivariate Cox proportional risk regression models were used to examine the association between HRR and all-cause mortality. The non-linear relationship between HRR and all-cause mortality was confirmed using a Cox proportional risk regression model fitted by cubic spline function and smooth curve fitting.
resultsA total of 246/1018 patients (24.17%) died. The serum HRR values were negatively associated with 180-day all-cause mortality (hazard ratio (HR) 0.80, 95% confidence interval (CI) 0.68-0.94). A two-piecewise regression model was used to obtain a threshold inflection point value of 9.74. The HR and the 95% CI on the left inflection point were 0.73 and 0.61-0.87 (p = 0.0005); on the right inflection point they were 1.06 and 0.82-1.38 (p = 0.6383).
conclusionThe relationship between all-cause mortality and the HRR values was non-linear in ischemic stroke patients with AF. All-cause mortality and HRR values were negatively correlated when the HRR value was ≤9.74.
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