ReviewBulletin of the National Research Centre2022
In vitro strategies for the enhancement of secondary metabolite production in plants: a review.
Review in Bulletin of the National Research Centre, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 142 citations in OpenAlex.
- An aromatic substrate prenyltransferase involved in the chemical diversification of flavonoids in Glycyrrhiza glabra.Planta · 2026Article
- Comparative Biochemistry of Wild and In Vitro-PropagatedLife (Basel, Switzerland) · 2026Article
- Temperature-Associated Anatomical, Photosynthetic, and Putative GC-MS Metabolomic Profiles in the Arid SpeciesMetabolites · 2026Article
- Elicitor-Mediated Enhancement of Secondary-Metabolite Biosynthesis inPlants (Basel, Switzerland) · 2026Review
- Aqueous Incubation Reveals Transformation of Rosmarinic Acid in Medicinally Important Nepetoideae Species and Leads to Novel Bioactive Compounds.Pharmaceutics · 2026Article
- Gold nanoparticle-mediated elicitation enhances andrographolide biosynthesis via auxin signalling in optimized hairy root cultures of Andrographis paniculata.Protoplasma · 2026Article
- The JA-CsMYC2.1-CsNOMT-sakuranetin module contributes to differential anthracnose resistance inHorticulture research · 2026Article
- Molecular mechanisms and evolutionary adaptations of transporters for photosynthates and specialized metabolites in plants.Plant cell reports · 2026Review
- Enhancing antioxidant and bioactive metabolite production inRSC advances · 2026Article
- Article
- Antioxidant and Anti-Inflammatory Activity of Cell Suspension Culture Extracts ofInternational journal of molecular sciences · 2025Article
- Hybrid Poly(Lactic)-Chitosan Scaffold Intensifying In Situ Bioprocessing ofInternational journal of molecular sciences · 2025Article
- Metabolite characterization and in vitro antiplasmodial potential assessment of Sonchus arvensis L. callus under glutamine treatment.Scientific reports · 2025Article
- Enhancement of indigotin and indirubin production in root cultures of Isatis species by HScientific reports · 2025Article
- Biosynthesized sulfur nanoparticles: a novel strategy to enhance antioxidant secondary metabolites in Lotus arabicus L. callus cultures.BMC plant biology · 2025Article
- Media Composition Effects on Hairy Root Biomass and Tetrandrine Production inMolecules (Basel, Switzerland) · 2025Article
- The Good, the Bad, and the Epigenetic: Stress-Induced Metabolite Regulation and Transgenerational Effects.Epigenomes · 2025Review
- Plant-Derived Natural Products and Their Nano Transformation: A Sustainable Option Towards Desert Locust Infestations.ChemistryOpen · 2025Review
- Elicitor-driven enhancement of phenolic compounds in geranium callus cultures: phytochemical profiling via LC-MS/MS and biological activities.Frontiers in chemistry · 2025Article
- Ethanolic extract ofFrontiers in plant science · 2025Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPlants are the prime source of vital secondary metabolites (SMs) which are medicinally important for drug development, and these secondary metabolites are often used by plants in the various important tasks like defense against herbivory, interspecies defenses and against different types of stresses. For humans, these secondary metabolites are important as medicines, pigments, flavorings and drugs. Because most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction, these medicinal plants are getting endangered. MAIN BODY: Plant cell culture technologies are introduced as a viable mechanism for producing and studying SMs of plants. Various types of in vitro strategies (elicitation, hairy root culture system, suspension culture system, etc.) have been considerably used for the improvement of the production of SMs of plants. For the enhancement of SM production, suspension culture and elicitation are mainly used, but hairy root culture and other organ cultures are proved to satisfy the demand of secondary metabolites. Now, it is easy to control and manipulate the pathways that produce the plant secondary metabolites.
conclusionsTechniques like plant cell, tissue and organ cultures provide a valuable method for the production of medicinally significant SMs. In recent years, most of the in vitro strategies are used due to knowledge and regulation of SM pathway in commercially valuable plants. In future, these things will provide a valuable method to sustain the feasibility of medicinal plants as the renewable sources of medicinally important compounds, and these methods will provide successful production of desired, important, valuable and also unknown compounds.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.