Evidence map›Paper›PMID 35221622›Full record

Observational studyEthiopian journal of health sciences2021

Neuroimaging Features and Associated Factors in Multiple Sclerosis Patients: A Perspective from a Private Care Center in Addis Ababa, Ethiopia.

Biniyam A Ayele, Mehila Z Wuhib, Betesaida G Zenebe, Yared Z Zewde, Yonas T Wolde, Guta Z Metaferia

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Ethiopian journal of health sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Biniyam A AyeleAssistant Professor of Neurology, Department of Neurology College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Mehila Z WuhibYehuleshet Specialty Clinic, Honorary Assistant Professor of Neurology.
Betesaida G ZenebeYehuleshet Specialty Clinic, Addis Ababa, Ethiopia.
Yared Z ZewdeAssistant Professor of Neurology, Department of Neurology College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Yonas T WoldeAssistant Professor of Radiology, Neuroradiologist Department of Radiology, St.Paul Millennium Medical College, Addis Ababa, Ethiopia.
Guta Z MetaferiaAssistant Professor of Neurology, Department of Neurology College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBrain and spine magnetic resonance image (MRI) have an invaluable importance in diagnosing multiple sclerosis (MS) in low prevalence countries such as Ethiopia. The objective of our study was to characterize the neuroimaging features and associated factors in Multiple sclerosis patients in Addis Ababa, Ethiopia.

methodA cross-sectional observational study was conducted in 30 multiple sclerosis patients at Yehuleshet Specialty Clinic, Addis Ababa, Ethiopia. Both descriptive and analytical statistics were used to analyze the data.

resultsWe have enrolled 30 patients with confirmed multiple sclerosis and clinically isolate syndrome. The mean age was 34.7 years (1SD=8.9). Female accounted 86.7%. The mean duration of illness was 3.4 years (1SD=3.1) (range: 1 - 11 years). Relapsing and remitting variant was the commonest sub type (66.7%). Alcohol use and head injury were the commonest identified risk factors reported by the patients. Classical radiological features of MS such as white matter lesions involving juxtacortical, U-fiber, corpus callosum (CC), and Dawson's finger projections pattern were observed in 46.7%, 23.3%, 70%, and 40% respectively. Cervical and thoracic cords were affected in 40% and 6.7% respectively. Global cortical and CC atrophy was observed in 16.7% and 6.7% respectively. Advanced age was associated with lesions of corpus callosum when adjusted for duration of illness and history of head injury (AOR 1.13, 95% CI 1.01-1.28, p=0.04).

conclusionTypical neuroimaging features of MS were prevalent among Ethiopian MS patients. Age was an independent predictor of lesions involving corpus callosum. Global cortical atrophy was common among Ethiopian MS patients.

Indexed as

Multiple SclerosisAdultCross-Sectional StudiesEthiopiaFemaleHumansMagnetic Resonance ImagingNeuroimagingDawson's finger projectionsEthiopiamagnetic resonance imagingMS-related lesionsMultiple sclerosis

Identifiers

PMID35221622
PMCPMC8843137

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