Evidence map›Paper›PMID 35221493›Full record

ArticleJournal of toxicologic pathology2022

Generation of a uniform thymic malignant lymphoma model with C57BL/6J

Susu Liu, Jianjun Lyu, Qianqian Li, Xi Wu, Yanwei Yang, Guitao Huo, Qingfen Zhu, Ming Guo, Yuelei Shen, Sanlong Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicologic pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Animal models for COVID-19: advances, gaps and perspectives.Signal transduction and targeted therapy · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Susu LiuDivision of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing Daxing district, Beijing 102629, China.
Jianjun LyuDepartment of Pathology, InnoStar Bio-tech Nantong Co., Ltd., Nantong 226133, China.
Qianqian LiNational Centre for Safety Evaluation of Drugs, Institute for Food and Drug Safety Evaluation, National Institutes for Food and Drug Control, A8 Hongda Middle Street, Beijing Economic-Technological Development Area, Beijing 100176, China.
Xi WuDivision of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing Daxing district, Beijing 102629, China.
Yanwei YangNational Centre for Safety Evaluation of Drugs, Institute for Food and Drug Safety Evaluation, National Institutes for Food and Drug Control, A8 Hongda Middle Street, Beijing Economic-Technological Development Area, Beijing 100176, China.
Guitao HuoNational Centre for Safety Evaluation of Drugs, Institute for Food and Drug Safety Evaluation, National Institutes for Food and Drug Control, A8 Hongda Middle Street, Beijing Economic-Technological Development Area, Beijing 100176, China.
Qingfen ZhuShandong Institute for Food and Drug Control, No. 2749, Xinluo Road, High-tech Zone, Jinan 250101, China.
Ming GuoShandong Institute for Food and Drug Control, No. 2749, Xinluo Road, High-tech Zone, Jinan 250101, China.
Yuelei ShenBeijing Biocytogen Co. LTD, No. 88 Kechuang 6th Avenue Ludong Area Economic-Technological Development Area, Beijing 101111, China.
Sanlong WangNational Centre for Safety Evaluation of Drugs, Institute for Food and Drug Safety Evaluation, National Institutes for Food and Drug Control, A8 Hongda Middle Street, Beijing Economic-Technological Development Area, Beijing 100176, China.
Changfa FanDivision of Animal Model Research, Institute for Laboratory Animal Resources, National Institutes for Food and Drug Control, No. 31 Huatuo Road, Beijing Daxing district, Beijing 102629, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoma is the third most common cancer diagnosed in children, and T-cell lymphoma has the worst prognosis based on clinical observations. To date, a lymphoma model with uniform penetrance has not yet been developed. In this study, we generated a

Indexed as

C57BL/6J genetic backgroundlymphoma modelMNU inductionp53 deficient mouseT cell lineage

Identifiers

PMID35221493
PMCPMC8828615

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.