ArticleJournal of molecular structure2022
Synthesis, kinetic evaluation and molecular docking studies of donepezil-based acetylcholinesterase inhibitors.
Article in Journal of molecular structure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 50 citations in OpenAlex.
- Bio-Based Potential of Phenolic-Rich Fabaceae Seeds (Gonocytisus angulatus, Podocytisus caramanicus): Chemical Standardization, Functional Screening, and Molecular Insights.Chemistry & biodiversity · 2026Article
- A predictive acetylcholinesterase inhibition model: an integrated computational approach on alkaloids and synthetic derivatives.Molecular diversity · 2026Article
- Identification of quinolinyl-containing dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors with moderate potency towards acetylcholinesterase.Results in chemistry · 2026Article
- Chemical and enantioselective GC-MS characterization ofFrontiers in pharmacology · 2026Article
- Electrochemical synthesis of spirooxindole-pyranopyrazole and spirooxindole-chromene derivatives as inhibitors of acetylcholinesterase.BMC chemistry · 2025Article
- Identification of Novel Bioactive Molecules in Black Chiloe's Giant Garlic (Antioxidants (Basel, Switzerland) · 2025Article
- Evaluation of novel nitrophenol-triazole hybrid molecules: biological screening and computational profiling.Future medicinal chemistry · 2025Article
- Structural Bioinformatics Applied to Acetylcholinesterase Enzyme Inhibition.International journal of molecular sciences · 2025Review
- Determination of Potential Lead Compound fromInternational journal of molecular sciences · 2024Article
- Analysis of Chemical Composition, Antioxidant Activity, and Toxicity of Essential Oil fromMolecules (Basel, Switzerland) · 2024Article
- Enhanced Antioxidant and Neuroprotective Properties of Pterostilbene (Resveratrol Derivative) in Amorphous Solid Dispersions.International journal of molecular sciences · 2024Article
- Convenient synthesis and in vitro activity of oxalyl bis(benzenesulfonylhydrazides) and related compounds.Results in chemistry · 2023Article
- Sahlep (Molecules (Basel, Switzerland) · 2022Article
- Article
- Recent developments in the design and synthesis of benzylpyridinium salts: Mimicking donepezil hydrochloride in the treatment of Alzheimer's disease.Frontiers in chemistry · 2022Review
- Design, synthesis, crystal structure,RSC advances · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
In an effort to develop new therapeutic agents to treat Alzheimer's disease, a series of donepezil-based analogs were designed, synthesized using an environmentally friendly route, and biologically evaluated for their inhibitory activity against electric eel acetylcholinesterase (AChE) enzyme.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.