ArticleBMC public health2022
Impact of the COVID-19 pandemic on Bordetella pertussis infections in England.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 66 citations in OpenAlex.
- Maternal pertussis immunization and the blunting of routine vaccine effectiveness: a meta-analysis and modeling study.Nature communications · 2024Pooled it
- The association between vaccine hesitancy and pertussis: a systematic review and meta-analysis.Italian journal of pediatrics · 2023Pooled it
- Impact of the COVID-19 pandemic on the global burden of pertussis: An analysis of trends and the emergence of an immunity gap.Human vaccines & immunotherapeutics · 2026Article
- Epidemiological characteristics and vaccination history analysis of pertussis in Quzhou from 2005 to 2024.Journal of health, population, and nutrition · 2026Article
- Surveillance and vaccine effectiveness of pertussis, the Netherlands, 2012 to 2024, with an unprecedented surge in 2023 and 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- The evolution of pertactin expression in Belgian circulatingMicrobiology spectrum · 2026Article
- Molecular surveillance of Bordetella pertussis during the 2024 outbreak in Southeast Brazil: allelic profiles and comparison to vaccine strain.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026Article
- Pertussis-SARS-CoV-2 Co-infection in Infants at Mohammed VI University Hospital, Marrakech, Morocco.Cureus · 2026Article
- Comparing Respiratory Illness Surveillance Case Definitions to Detect Bordetella pertussis in Children Aged <5 Years With Respiratory Illness in South Africa, 2017-2023.The Journal of infectious diseases · 2026Article
- Parent-driven transmission, off-label SMZ-TMP, and severe pertussis prediction in infants under 2 months: a real-world observational cohort of 527 cases.Frontiers in pediatrics · 2026Article
- Resurgence of pertussis: Epidemiological trends, contributing factors, challenges, and recommendations for vaccination and surveillance.Human vaccines & immunotherapeutics · 2025Review
- Pertussis epidemiological surveillance and immunization history in children under five years in a megacity in China from 2019 to 2023.Human vaccines & immunotherapeutics · 2025Article
- Positivity analysis ofMicrobiology spectrum · 2025Article
- Natural immune boosting biases pertussis infection estimates in seroprevalence studies.Nature communications · 2025Article
- Increased Pneumonia-Related Emergency Department Visits, Northern Italy.Emerging infectious diseases · 2025Article
- Whooping cough in the most vulnerable: A case series of pertussis in infants younger than three months in Qatar.Qatar medical journal · 2025Article
- Pertussis resurgence: epidemiological trends, pathogenic mechanisms, and preventive strategies.Frontiers in immunology · 2025Review
- Public health management of pertussis in adults: Practical challenges and future strategies.Human vaccines & immunotherapeutics · 2024Review
- Epidemiological characteristics and survival analysis of pertussis in Quzhou.Human vaccines & immunotherapeutics · 2024Article
- Pertussis vaccines, epidemiology and evolution.Nature reviews. Microbiology · 2024Review
Corrections and comments
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Authors and funding
9 authors at 1 institution.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn March 2020, England went into its first lockdown in response to the COVID-19 pandemic. Restrictions eased temporarily, followed by second and third waves in October 2020 and January 2021. Recent data showed that the COVID-19 pandemic resulted in reduced transmission of some invasive diseases. We assess the impact of the COVID-19 pandemic on pertussis incidence and on the immunisation programme in England.
methodsWe assessed trends in pertussis cases from 2012 to 2020 by age group and month. Incidence from the time that England eased its initial lockdown measures in July 2020 through to summer 2021 was calculated and the incidence rate ratios of pertussis cases from five years prior to the pandemic (July 2014 - June 2019) compared to the same time period during the pandemic (July 2020 - June 2021). Vaccine coverage estimates for pertussis containing vaccines were reviewed for the maternal and childhood programmes.
resultsA substantial decline in pertussis cases was observed from April 2020 onwards, marking the lowest number of cases in the last decade. Pertussis incidence dropped in all age groups, particularly among infants less than one year old (0.50 / 100,000 during July 2020 to June 2021 compared to 24.49/ 100,000 from July 2014 to June 2019). The incidence rate ratio was 0.02 (95% CI 0.01 to 0.02) for July 2014 to June 2019 (pre-pandemic) compared to the pandemic period of July 2020 to June 2021. None of the cases had a co-infection with SARS-CoV-2. Vaccine coverage for infants born between January to March 2020 with three doses of pertussis vaccine by 12 months of age decreased by 1.1% points compared to infants born between January to March 2019 (91.6% and 92.7%, respectively). Prenatal pertussis coverage for the 2020 to 2021 financial year was 2.7% points lower than the year prior to the pandemic (70.5% and 76.8%, respectively).
conclusionsLockdown measures due to the COVID-19 pandemic have had a significant impact on pertussis transmission. With the easing of restrictions it is important to continue monitoring pertussis cases in England alongside coverage of the maternal and childhood immunisation programmes.
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