Evidence map›Paper›PMID 35220938›Full record

Trial reportBMC medical research methodology2022

Locating and testing the healthy context paradox: examples from the INCLUSIVE trial.

G J Melendez-Torres, Emily Warren, Obioha C Ukoumunne, Russell Viner, Chris Bonell

Abstract readClinical Trial
In one paragraph

Trial report in BMC medical research methodology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

G J Melendez-TorresPeninsula Technology Assessment Group, University of Exeter Medical School, Exeter, UK. g.j.melendez-torres@exeter.ac.uk.
Emily WarrenDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.
Obioha C UkoumunneNIHR Applied Research Collaboration South West Peninsula (PenARC), University of Exeter Medical School, Exeter, UK.
Russell VinerDepartment of Social Science, UCL Institute of Child Health, London, UK.
Chris BonellDepartment of Public Health, Environments and Society, London School of Hygiene and Tropical Medicine, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe healthy context paradox, originally described with respect to school-level bullying interventions, refers to the generation of differences in mental wellbeing amongst those who continue to experience bullying even after interventions successfully reduce victimisation. Using data from the INCLUSIVE trial of restorative practice in schools, we relate this paradox to the need to theorise potential harms when developing interventions; formulate the healthy context paradox in a more general form defined by mediational relationships and cluster-level interventions; and propose two statistical models for testing the healthy context paradox informed by multilevel mediation methods, with relevance to structural and individual explanations for this paradox.

methodsWe estimated two multilevel mediation models with bullying victimisation as the mediator and mental wellbeing as the outcome: one with a school-level interaction between intervention assignment and the mediator; and one with a random slope component for the student-level mediator-outcome relationship predicted by school-level assignment. We relate each of these models to contextual or individual-level explanations for the healthy context paradox.

resultsNeither model suggested that the INCLUSIVE trial represented an example of the healthy context paradox. However, each model has different interpretations which relate to a multilevel understanding of the healthy context paradox.

conclusionsGreater exploration of intervention harms, especially when those accrue to population subgroups, is an essential step in better understanding how interventions work and for whom. Our proposed tests for the presence of a healthy context paradox provide the analytic tools to better understand how to support development and implementation of interventions that work for all groups in a population.

trial registrationCurrent Controlled Trials, ISRCTN10751359 .

Indexed as

BullyingHealth StatusHumansSchoolsStudentsBullyingCluster-randomised trialsContextual effectsIntervention harmsMental wellbeing

Identifiers

PMID35220938
PMCPMC8883633

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.