Observational studyBMC nephrology2022
Central venous pressure and acute kidney injury in critically ill patients with multiple comorbidities: a large retrospective cohort study.
Observational study in BMC nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Observational
- Re-exploring the association between the central venous pressure and the risk of sepsis-associated acute kidney injury according to the latest definition: Analysis of the MIMIC-IV database.Pakistan journal of medical sciences · 2025Article
- The Association Between Central Venous Pressure and Acute Kidney Injury Development in Patients with Septic Shock.Journal of clinical medicine · 2025Article
- Acute kidney injury after lung transplantation, incidence, risk factors, and effects: A Swedish nationwide study.Acta anaesthesiologica Scandinavica · 2025Article
- Impact of early CVP monitoring on 1-year mortality in patients with congestive heart failure in the ICU: a retrospective analysis based on the MIMIC-IV2.2 database.BMC cardiovascular disorders · 2025Article
- Central Venous Pressure as a Predictor of Acute Kidney Injury in Cardiac Surgery: A Systematic Review of Observational Studies.Diagnostics (Basel, Switzerland) · 2025Review
- Point-of-Care Ultrasonography and Worsening of Renal Function in Acute Heart Failure: A Cohort Study.Canadian journal of kidney health and disease · 2025Article
- The right heart perspective in chronic cardiorenal syndrome: the key role of right heart function and tricuspid regurgitation innovation.Frontiers in cardiovascular medicine · 2025Review
- The outcomes of a standardized protocol for extracorporeal mechanical circulatory support selection-left ventricular challenge protocol.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2024Article
- SGLT2 Inhibitors and the Risk of Contrast-Associated Nephropathy Following Angiographic Intervention: Contradictory Concepts and Clinical Outcomes.International journal of molecular sciences · 2024Review
- Association between the mean perfusion pressure and the risk of acute kidney injury in critically ill patients with sepsis: a retrospective cohort study.BMC infectious diseases · 2024Article
- Breaking Under Pressure: Cardiorenal Syndrome and Elevated Central Venous Pressures in Children With Heart Disease.JACC. Advances · 2024Article
- Venous congestion in septic shock quantified with point-of-care ultrasound: a pilot prospective multicentre cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024Observational
- Intraoperative central venous pressure during cardiopulmonary bypass is an alternative indicator for early prediction of acute kidney injury in adult cardiac surgery.Journal of cardiothoracic surgery · 2024Article
- Bidirectional pressure: a mini review of ventilator-lung-kidney interactions.Frontiers in physiology · 2024Review
- SGLT2 inhibitors in the treatment of type 2 cardiorenal syndrome: Focus on renal tubules.Frontiers in nephrology · 2022Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the traditional acceptance of higher central venous pressure (CVP) levels, clinicians ignore the incidence of acute kidney injury (AKI). The objective of this study was to assess whether elevated CVP is associated with increased AKI in critically ill patients with multiple comorbidities.
methodsThis was a retrospective observational cohort study using data collected from the Medical Information Mart for Intensive Care (MIMIC)-III open-source clinical database (version 1.4). Critically ill adult patients with CVP and serum creatinine measurement records were included. Linear and multivariable logistic regression were performed to determine the association between elevated CVP and AKI.
resultsA total of 11,135 patients were enrolled in our study. Critically ill patients in higher quartiles of mean CVP presented greater KDIGO AKI severity stages at 2 and 7 days. Linear regression showed that the CVP quartile was positively correlated with the incidence of AKI within 2 (R
conclusionsElevated CVP is associated with an increased risk of AKI in critically ill patients with multiple comorbidities. The optimal CVP should be personalized and maintained at a low level to avoid AKI in critical care settings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.