Evidence map›Paper›PMID 35220902›Full record

ArticleAutophagy2022

The Crohn Disease-associated ATG16L1

Ping Gao, Hongtao Liu, Huarong Huang, Yu Sun, Baoqian Jia, Baidong Hou, Xuyu Zhou, Warren Strober, Fuping Zhang

Open access · greenAbstract read
In one paragraph

Article in Autophagy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
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  3. Regulation of Innate Immune Signaling by Autophagy.International journal of molecular sciences · 2026
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  14. hLife · 2025
    Article
  15. Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ping GaoCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Hongtao LiuCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Huarong HuangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Yu SunCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Baoqian JiaCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Baidong HouKey Laboratory of Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China.
Xuyu ZhouCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.
Warren StroberMucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, Maryland, USA.
Fuping ZhangCAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences (CAS), Beijing, China.ORCID 0000-0001-8511-2885
Chinese Academy of Sciences · CNNational Institutes of Health · US

Funding

Immunoregulatory Defects In Inflammatory Bowel DiseaseZIAAI000354 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI STROBER, WARREN · 2009 to 2025
$8.7M
6 · The paper itself

Abstract

The mechanisms by which the ATG16L1

Indexed as

AutophagyCrohn DiseaseAnimalsAutophagy-Related ProteinsFibroblastsLipopolysaccharidesMiceNF-kappa BSequestosome-1 ProteinTNF Receptor-Associated Factor 6Atg16l1 protein, mouseAutophagy-Related ProteinsLipopolysaccharidesNF-kappa BSequestosome-1 ProteinTNF Receptor-Associated Factor 6ATG16L1T300AautophagyNFKBNLRTLR4

Identifiers

PMID35220902
PMCPMC9629077
OpenAlexW4214749569

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.