Evidence map›Paper›PMID 35220855›Full record

ArticleRenal failure2022

Patients receiving hemodialysis do not lose SARS-CoV-2 antibodies more rapidly than non-renal controls: a prospective cohort study.

Ekaterina Parshina, Alexey Zulkarnaev, Alexey Tolkach, Andrey Ivanov, Pavel Kislyy, Abduzhappar Gaipov

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In one paragraph

Article in Renal failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ekaterina ParshinaDepartment of Nephrology and Dialysis, Saint-Petersburg State University Hospital, Saint-Petersburg, Russia.ORCID 0000-0003-3625-1824
Alexey ZulkarnaevSurgical Department of Transplantology and Dialysis, Moscow Regional Research and Clinical Institute ("MONIKI"), Moscow, Russia.ORCID 0000-0001-5405-7887
Alexey TolkachDepartment of Nephrology and Dialysis, Saint-Petersburg State University Hospital, Saint-Petersburg, Russia.ORCID 0000-0003-4483-6654
Andrey IvanovHuman Genetics Department, Saint Petersburg State University Hospital, Saint-Petersburg, Russian Federation.ORCID 0000-0002-1676-7754
Pavel KislyyDepartment of Nephrology and Dialysis, Saint-Petersburg State University Hospital, Saint-Petersburg, Russia.ORCID 0000-0003-0745-8260
Abduzhappar GaipovDepartment of Medicine, Nazarbayev University School of Medicine, Nur-Sultan, Kazakhstan.ORCID 0000-0002-9844-8772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatients with end-stage kidney disease receiving maintenance hemodialysis (HD) are at increased risk for mortality after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) compared with the general population. However, it is currently unknown whether the long-term SARS-CoV-2 humoral and cellular immune responses in patients receiving HD are comparable to individuals with normal kidney function.

methodThe prospective cohort study included 24 patients treated with maintenance HD and 27 non-renal controls with confirmed history of coronavirus disease (COVID-19). In all participants the levels of specific IgG were quantified at three timepoints: 10, 18, and 26 weeks from disease onset. In a subgroup of patients, specific T-cell responses were evaluated.

resultsThe seropositivity rate declined in controls over time and was 85% and 70.4% at weeks 18 and 26, respectively. All HD patients remained seropositive over the study period. Seropositivity rate at week 26 was greater among patients receiving HD: RR = 1.4 [95%CI: 1.17-1.94] (reciprocal of RR = 0.7 [95% CI: 0.52-0.86]),

conclusionCompared with non-renal adults, patients receiving HD maintain significant long-term humoral and cellular immune responses following natural COVID-19.

Indexed as

Renal DialysisAdultAntibodies, ViralCase-Control StudiesCOVID-19HumansImmunity, CellularImmunity, HumoralImmunoglobulin GKidney Failure, ChronicMiddle AgedProspective StudiesRisk FactorsSARS-CoV-2T-LymphocytesAntibodies, ViralImmunoglobulin Gantibodycellular immunityCOVID-19hemodialysisSARS-CoV-2

Identifiers

PMID35220855
PMCPMC8890585

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.