Evidence map›Paper›PMID 35220781›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Macrophage polarization in hypoxia and ischemia/reperfusion: Insights into the role of energetic metabolism.

Elmira I Yakupova, Grigoriy V Maleev, Andrei V Krivtsov, Egor Y Plotnikov

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

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  5. [Lactate induces gastric mucosal injury by promoting M1 polarization of macrophagesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Elmira I YakupovaA.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119234, Russia.
Grigoriy V MaleevInstitute of Physiologically Active Compounds, Russian Academy of Sciences, Chernogolovka 142432, Russia.
Andrei V KrivtsovCenter for Pediatric Cancer Therapeutics, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.
Egor Y PlotnikovA.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119234, Russia.ORCID 0000-0003-2838-3704
Lomonosov Moscow State University · RUHarvard University · USInstitute of Physiologically Active Compounds · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages, the key cells of innate immunity, possess wide phenotypical and functional heterogeneity.

Indexed as

Cell PolarityMacrophage ActivationHumansHypoxiaIschemiaMacrophagesReperfusionenergy metabolismhypoxiaischemiaM1–M2 macrophage polarizationMacrophagesmetabolism

Identifiers

PMID35220781
PMCPMC9189569
OpenAlexW4214758094

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.