Evidence map›Paper›PMID 35220630›Full record

ArticleJournal of cardiac surgery2022

Contemporary prevalence and outcomes of rheumatic mitral valve surgery.

Robert B Hawkins, Raymond J Strobel, J Hunter Mehaffey, Mohammed A Quader, Mark Joseph, Gorav Ailawadi

Abstract read
In one paragraph

Article in Journal of cardiac surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Robert B HawkinsDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0002-3959-8201
Raymond J StrobelDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia, USA.
J Hunter MehaffeyDivision of Thoracic and Cardiovascular Surgery, University of Virginia, Charlottesville, Virginia, USA.ORCID https://orcid.org/0000-0002-0612-7737
Mohammed A QuaderDivision of Cardiothoracic Surgery, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID https://orcid.org/0000-0001-8290-043X
Mark JosephDivision of Cardiovascular and Thoracic Surgery, Carilion Clinic/Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA.ORCID https://orcid.org/0000-0003-2951-9343
Gorav AilawadiDepartment of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan, USA.

Funding

NIH National Heart, Lung, and Blood Institute
6 · The paper itself

Abstract

objectiveRheumatic mitral valve disease is often viewed as a historic disease in North America with limited contemporary data. We hypothesized that rheumatic pathology remains common and has worse short-term outcomes and higher resource utilization compared to other mitral valve pathologies.

methodAll patients undergoing mitral valve repair or replacement (2011-2019) were extracted from a regional Society of Thoracic Surgeons database. Resource utilization metrics included inflation-adjusted hospital costs. Patients were stratified by mitral valve pathology for univariate analysis.

resultOut of the 6625 mitral valve procedures, 835 (12.6%) were from rheumatic disease, a proportion that incrementally increased over time (+0.39% per year, p = .032). Among 19 hospitals, there was high variability in number of rheumatic mitral operations (median: 22, interquartile range [IQR]: 5-80) and rate of rheumatic repairs (median: 3%, IQR: 0%-6%). Rheumatic patients were younger (62 vs. 65, p < .0001), more often female (75% vs. 43%, p < .001) and with greater burden of heart failure, multi-valve disease, and lung disease, but less coronary disease. There were no differences in operative mortality (5.2% vs. 5.0%, p = .85) or major morbidity (22.2% vs. 21.8%, p = .83). However, resource utilization was higher for rheumatic patients, including more frequent transfusions (43% vs. 39%, p = .012), longer ICU (73 vs. 64 h, p < .0001) and postoperative length of stay (8 vs. 7 days, p < .0001).

conclusionsRheumatic mitral disease accounts for a meaningful (12%) and rising percentage of mitral valve operations in the region, with high variability among hospitals. Rheumatic mitral surgery yielded similar short-term outcomes compared to nonrheumatic pathology, but required greater resource utilization.

Indexed as

Cardiac Surgical ProceduresHeart Valve Prosthesis ImplantationFemaleHumansMitral ValvePrevalenceTreatment Outcomemitral valveoutcomes researchresource utilizationrheumatic disease

Identifiers

PMID35220630
PMCPMC9303441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.