ReviewPain and therapy2022
Pain in Intensive Care: A Narrative Review.
Review in Pain and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Living with pain-a systematic review on patients' subjective experiences.Systematic reviews · 2025Pooled it
- Hemodynamic Effects of Anesthetics, Sedatives, and Analgesics in the CICU: Clinical Decision Guidance.JACC. Advances · 2026Review
- Emerging technologies in interventional pain management: a scoping review on current innovations and future directions.BMC anesthesiology · 2026Article
- Traumatic memories and nursing experiences of ICU discharged patients: a systematic review and meta-synthesis of qualitative studies.BMC nursing · 2026Article
- Evidence of internal structure validity of the nursing outcome "Mechanical Ventilation Weaning Response: Adult (0412)" for critically ill COVID-19 patients.International journal of nursing knowledge · 2026Article
- Pain Management Frameworks and Critical Care Nursing Competencies: An Evidence-Informed Integrative Review.Cureus · 2026Review
- Postoperative Pain and Opioid Use Following Lower-Limb Escharectomy and Skin Grafting Under a Standardized Regional Anesthesia Protocol: A Retrospective Study.Life (Basel, Switzerland) · 2026Article
- Long-term mental health change patterns in ICU survivors: a four-year comparative follow-up from the SMAP-HoPe study.Journal of intensive care · 2025Article
- Severity and factors associated with pain in patients on mechanical ventilators in Amhara region, North-West Ethiopia: a multi-center prospective observational study.Scientific reports · 2025Observational
- Influencing factor analysis and clinical efficacy of early intervention in severe acute pancreatitis with persistent organ failure.Scientific reports · 2025Observational
- Identifying essential medications for critical care: initial findings from US academic intensive care units.Journal of pharmaceutical policy and practice · 2025Article
- A retrospective review of advanced life support interfacility transfers of the public sector emergency medical service in the Western Cape Province, South Africa.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025Article
- Comparison of Oliceridine to Remifentanil for Optimal Analgesia in Mechanical Ventilation (CO-ROAM): Study Protocol for a Multicenter Randomized Controlled Trial.Pain and therapy · 2024Article
- Use of high flow nasal cannula in critical burn patient during deep sedation in enzymatic bromelain debridement (nexobridAnnals of burns and fire disasters · 2024Article
- Challenges of the Regional Anesthetic Techniques in Intensive Care Units - A Narrative Review.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2024Review
- Pain Management Strategies in Intensive Care Unit: Challenges and Best Practice.Galen medical journal · 2024Article
- Effectiveness of Nurse-led Interventions on Pain and Complications among Patients Admitted to Intensive Care Unit: A Quasi-experimental study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care MedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
All critically ill adult patients in intensive care units (ICU) typically experience pain. Critically ill adults suffer pain of different intensities. It depends on individual characteristics, specific procedural interventions, and underlying diseases. Inadequate management of acute pain is a risk factor for the emergence of chronic pain, where the incidence is up to 33% into the ICU survivor population. For the management of pain, agitation, and delirium, several coexisting clinical practice guidelines have been published. The first problem is that the patient recovered in intensive care unit should not be able to communicate its pain state. Opioids are the analgesic drugs of choice in critically ill patients with non-neuropathic pain. All intravenous opioids have the same effects, respecting the equianalgesic table. Observational research has shown that opioids are the main analgesic treatment in over 80% of mechanically ventilated patients. It is interesting that opioid consumption in an ICU and the memory of painful experience are linked to the development of post-traumatic stress disorder after ICU discharge. In order to reduce the side effects and maintain analgesia, it is useful to associate adjuvant medications with opioids. An opportunity to improve patients' experience in an ICU is to manage pain through multimodal approaches.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.