ArticleTheoretical medicine and bioethics2021
Is the replication crisis a base-rate fallacy?
Article in Theoretical medicine and bioethics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Replication of Sensor-Based Categorization of Upper-Limb Performance in Daily Life in People Post Stroke and Generalizability to Other Populations.Sensors (Basel, Switzerland) · 2025Article
- Philosophy of medicine in 2021.Theoretical medicine and bioethics · 2021Article
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Authors and funding
1 author.
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Abstract
Is science in the midst of a crisis of replicability and false discoveries? In a recent article, Alexander Bird offers an explanation for the apparent lack of replicability in the biomedical sciences. Bird argues that the surprise at the failure to replicate biomedical research is a result of the fallacy of neglecting the base rate. The base-rate fallacy arises in situations in which one ignores the base rate-or prior probability-of an event when assessing the probability of this event in the light of some observed evidence. By extension, the replication crisis would result from ignoring the low prior probability of biomedical hypotheses. In this paper, my response to Bird's claim is twofold. First, I show that the argument according to which the replication crisis is due to the low prior of biomedical hypotheses is incomplete. Second, I claim that a simple base-rate fallacy model does not account for some important methodological insights that have emerged in discussions of the replication crisis.
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