Evidence map›Paper›PMID 35220465›Full record

ArticleAnalytical and bioanalytical chemistry2022

Simplified screening approach of anabolic steroid esters using a compact atmospheric solid analysis probe mass spectrometric system.

Ane Arrizabalaga-Larrañaga, Paul W Zoontjes, Johan J P Lasaroms, Michel W F Nielen, Marco H Blokland

Open access · hybridAbstract read
In one paragraph

Article in Analytical and bioanalytical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ane Arrizabalaga-LarrañagaDepartment of Chemical Engineering and Analytical Chemistry, University of Barcelona, Av. Diagonal 645, 08028, Barcelona, Spain. a.arrizabalaga@ub.edu.
Paul W ZoontjesWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, 6700 AE, Wageningen, The Netherlands.
Johan J P LasaromsWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, 6700 AE, Wageningen, The Netherlands.
Michel W F NielenWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, 6700 AE, Wageningen, The Netherlands.
Marco H BloklandWageningen Food Safety Research (WFSR), Part of Wageningen University & Research, P.O. Box 230, 6700 AE, Wageningen, The Netherlands.
Wageningen University & Research · NLUniversitat de Barcelona · ES

Funding

Dutch Ministry of Agriculture, Nature and Food Quality KB-23-002-005
6 · The paper itself

Abstract

Due to the absence of chromatographic separation, ambient ionization mass spectrometry had the potential to improve the throughput of control laboratories in the last decades and will soon be an excellent approach for on-site use as well. In this study, an atmospheric solids analysis probe (ASAP) with a single quadrupole mass analyzer has been evaluated to identify anabolic steroid esters rapidly. Sample introduction, applied scan time, and probe temperature were optimized for sensitivity. The in-source fragmentations of seventeen selected steroid esters, commonly found in illicit samples, were determined by applying different cone voltages (12, 20, 30, and 40 V). A spectral library was created for these steroid esters based on the four stages of in-source fragmentation spectra. The applicability of this method was demonstrated for the rapid identification of steroid esters in oily injection solutions, providing test results in less than 2 min.

Indexed as

Anabolic AgentsEstersMass SpectrometrySteroidsTestosterone CongenersAnabolic AgentsEstersSteroidsTestosterone CongenersAmbient ionizationAtmospheric solids analysis probeMass spectrometryOn-site testingTransportable MS

Identifiers

PMID35220465
PMCPMC9018663
OpenAlexW4214533131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.