Evidence map›Paper›PMID 35220442›Full record

Trial reportEuropean journal of nutrition2022

UVB-exposed wheat germ oil increases serum 25-hydroxyvitamin D

Anja C Bailer, Sophie Philipp, Shabnam Staudt, Thomas Weidauer, Michael Kiehntopf, Stefan Lorkowski, Gabriele I Stangl, Christine Dawczynski

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03499327 (Human Intervention Study to Increase 25-hydroxyvitamin D Levels by Regular Consumption of Wheat Germ Oil), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03499327 nacompletednot on this map

Human Intervention Study to Increase 25-hydroxyvitamin D Levels by Regular Consumption of Wheat Germ Oil (UV-treated) vs. Wheat Germ Oil Untreated (Control)

TypeinterventionalSponsorUniversity of JenaRan2018 to 2018Enrolled50ConditionsVitamin D3 DeficiencyArmsWheat germ oil (UV treated), Wheat germ oil (untreated)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Anja C BailerInstitute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Von-Danckelmann-Platz 2, 06120, Halle (Saale), Germany.
Sophie PhilippInstitute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Von-Danckelmann-Platz 2, 06120, Halle (Saale), Germany.
Shabnam StaudtCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Thomas WeidauerCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Michael KiehntopfInstitute of Clinical Chemistry and Laboratory Diagnostics, University Hospital Jena, 07747, Jena, Germany.
Stefan LorkowskiCompetence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany.
Gabriele I Stangl *Institute of Agricultural and Nutritional Sciences, Martin Luther University Halle-Wittenberg, Von-Danckelmann-Platz 2, 06120, Halle (Saale), Germany.
Christine Dawczynski *Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD) Halle-Jena-Leipzig, Jena, Germany. christine.dawczynski@uni-jena.de.ORCID http://orcid.org/0000-0002-4063-6199
Friedrich Schiller University Jena · DEMartin Luther University Halle-Wittenberg · DEJena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study investigated whether UVB-exposed wheat germ oil (WGO) is capable to improving the vitamin D status in healthy volunteers.

methodsA randomized controlled human-intervention trial in parallel design was conducted in Jena (Germany) between February and April. Ultimately, 46 healthy males and females with low mean 25-hydroxyvitamin D (25(OH)D) levels (34.9 ± 10.6 nmol/L) were randomized into three groups receiving either no WGO oil (control, n = 14), 10 g non-exposed WGO per day (- UVB WGO, n = 16) or 10 g WGO, which was exposed for 10 min to ultraviolet B-light (UVB, intensity 500-630 µW/cm

resultsParticipants who received the UVB-exposed WGO were characterized by an increase of circulating 25(OH)D

conclusionUVB-exposed WGO containing 23.7 µg vitamin D can increase 25(OH)D

trial registrationClinicalTrials.gov: NCT03499327 (registered, April 13, 2018).

Indexed as

ErgocalciferolsVitamin D Deficiency25-Hydroxyvitamin D 2CalcifediolCholecalciferolChromatography, LiquidFemaleHumansMalePlant OilsTandem Mass SpectrometryVitamin DVitamins25-hydroxyvitamin D25-Hydroxyvitamin D 2CalcifediolCholecalciferolErgocalciferolsPlant OilsVitamin DVitaminswheat germ oilHealthy subjectsRandomized controlled trialUVB-exposureVitamin D2Vitamin D statusWheat germ oil

Identifiers

PMID35220442
PMCPMC9279215
OpenAlexW4214553071

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.