Evidence map›Paper›PMID 35220305›Full record

ArticleNeonatology2022

Neonatal Cerebral Venous Thrombosis following Maternal SARS-CoV-2 Infection in Pregnancy.

Francesca Campi, Daniela Longo, Iliana Bersani, Immacolata Savarese, Giulia Lucignani, Cristina Haass, Maria Chiara Paolino, Sarah Vadalà, Paola De Liso, Matteo Di Capua and 5 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Neonatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. The Hemostatic System in Newborns and the Risk of Neonatal Thrombosis.International journal of molecular sciences · 2023
    Review
  4. Article
  5. A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Francesca CampiDepartment of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Daniela LongoNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Iliana BersaniDepartment of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Immacolata SavareseDepartment of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Giulia LucignaniNeuroradiology Unit, Imaging Department, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Cristina HaassNeonatal Intensive Care Unit, S. Pietro FBF Hospital, Rome, Italy.
Maria Chiara PaolinoNeonatal Intensive Care Unit, S. Pietro FBF Hospital, Rome, Italy.
Sarah VadalàNeonatal Intensive Care Unit, S. Pietro FBF Hospital, Rome, Italy.
Paola De LisoDivision of Neurology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Matteo Di CapuaDivision of Neurology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Matteo LucianiDepartment of Pediatric Hematology Oncology, Bambino Gesù Children Hospital IRCSS, Rome, Italy.
Giacomo EspositoNeurosurgery Unit, Department of Neuroscience and Neurorehabilitation, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Paolina Giuseppina AmanteNeurosurgery Unit, Department of Neuroscience and Neurorehabilitation, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Federico VigevanoDivision of Neurology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Andrea DottaDepartment of Medical and Surgical Neonatology, Bambino Gesù Children's Hospital IRCCS, Rome, Italy.
Bambino Gesù Children's Hospital · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITOspedale San Pietro Fatebenefratelli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A possible consequence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the development of an exacerbated thrombophilic status, and cerebral venous thrombosis (CVT) is a rare but possible complication of SARS-CoV-2 infection reported both in adults and in children. The present case report describes the clinical course of a term neonate showing extended CVT of unclear origin, whose mother had developed SARS-CoV-2 infection during the third trimester of pregnancy. We speculate that the prothrombotic status induced by maternal SARS-CoV-2 infection may have played a pathophysiological role in the development of such severe neonatal complication. Further investigations are required to confirm such hypothesis.

Indexed as

COVID-19Intracranial ThrombosisPregnancy Complications, InfectiousVenous ThrombosisAdultChildFamilyFemaleHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy OutcomeSARS-CoV-2Cerebral venous thrombosisMagnetic resonance imagingNeonatePregnancySARS-CoV-2

Identifiers

PMID35220305
PMCPMC9059005
OpenAlexW4214592668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.