Evidence map›Paper›PMID 35219998›Full record

ArticleDrug and alcohol dependence2022

Effects of intersecting internalized stigmas and avoidance on HIV and alcohol-related outcomes among people living with HIV in South Africa.

Kristen S Regenauer, Mary B Kleinman, Jennifer M Belus, Bronwyn Myers, John A Joska, Jessica F Magidson

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kristen S RegenauerDepartment of Psychology, University of Maryland, College Park, Maryland, United States. Electronic address: kregenau@umd.edu.
Mary B KleinmanDepartment of Psychology, University of Maryland, College Park, Maryland, United States.
Jennifer M BelusDepartment of Psychology, University of Maryland, College Park, Maryland, United States; Swiss Tropical and Public Health Institute, Department of Medicine, Basel, Switzerland; University of Basel, Basel, Switzerland.
Bronwyn MyersCurtin enAble Institute, Faculty of Health Sciences, Curtin University, Perth, Australia; Alcohol, Tobacco and Other Drug Abuse Research Unit, South African Medical Research Council, Tygerberg, South Africa; Division of Addiction Psychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
John A JoskaHIV Mental Health Research Unit, Division of Neuropsychiatry, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa.
Jessica F MagidsonDepartment of Psychology, University of Maryland, College Park, Maryland, United States.

Funding

Hybrid Effectiveness-Implementation Trial for ART Adherence and Substance Use in HIV Care in South AfricaK23DA041901 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F · 2016 to 2020
$1.0M
Training CHWs to Support Re-Engagement in TB/HIV Care in the Context of Depression and Substance UseR34MH122268 · NIMH · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F, MYERS, BRONWYN · 2020 to 2022
$606k
Evaluating the Role of Peers to Reduce Substance Use Stigma and Improve HIV Care Outcomes in South AfricaR21DA053212 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI MAGIDSON, JESSICA F, MYERS, BRONWYN · 2020 to 2021
$372k
NIDA NIH HHS K23 DA041901NIDA NIH HHS R21 DA053212NIMH NIH HHS R34 MH122268
6 · The paper itself

Abstract

backgroundDespite HIV and problematic drinking often co-occurring in South Africa (SA), limited research has examined how HIV stigma relates to alcohol outcomes, how alcohol stigma relates to HIV outcomes, and moderators of these associations. This study examined the intersection of HIV and alcohol stigmas on HIV and alcohol outcomes, and the role of avoidant behavior in moderating these relationships in SA.

methodsWe assessed biomarker-verified measures of antiretroviral therapy (ART) adherence, HIV viral load (VL), and alcohol consumption, and self-reported measures of internalized HIV/alcohol stigmas, avoidant behavior, ART adherence, and problematic drinking-alcohol use that will likely lead to health or other problems-cross-sectionally among people with HIV (PWH) and problematic drinking (N = 64). We conducted regression analyses with interaction terms.

findingsA significant relationship was found between internalized alcohol stigma and VL suppression, with higher levels of alcohol stigma associated with a lower likelihood of suppression (OR=1.68, 95%CI[1.11-2.65], p = .02). Avoidance significantly moderated the relationship between internalized HIV stigma and problematic drinking; higher HIV stigma was associated with lower problematic drinking only at low levels of avoidance (b(SE)= -1.92(.85), p = .03).

conclusionsThis study is the first to examine associations between HIV and alcohol stigmas, avoidance, and both HIV and alcohol outcomes in SA. Findings contribute to our understanding of how alcohol stigma relates to biological HIV outcomes, and the role of avoidance in the relationship between internalized HIV stigma and problematic drinking. Findings may inform future clinical interventions aiming to address the impact of stigma on HIV treatment outcomes and alcohol use among PWH in SA.

Indexed as

HIV InfectionsMedication AdherenceAnti-Retroviral AgentsHumansSocial StigmaSouth AfricaAnti-Retroviral AgentsAlcohol useAntiretroviral therapy (ART) adherenceGlobal mental healthHIVSouth AfricaStigma

Identifiers

PMID35219998
PMCPMC8978067

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.