SynthesisClinical psychology review2022
Emotion regulation as mediator between childhood adversity and psychopathology: A meta-analysis.
Synthesis in Clinical psychology review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 81 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Using Integrated Suicide and Trauma Therapy to Reduce Suicide Risk Among Adults With a History of Childhood Trauma
Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression: A Pilot Study
Who cites it
81 citing papers in PubMed, 6 syntheses or guidelines pooled it, 178 citations in OpenAlex.
- Psychological factors mediating/moderating the association between adverse childhood experiences and suicidal ideation in young people: a systematic review.European child & adolescent psychiatry · 2026Pooled it
- Emotion regulation impairment across psychiatric disorders: a systematic review and meta-analysis.Translational psychiatry · 2026Pooled it
- Global research landscape, knowledge structure, and emerging trends in adverse childhood experiences and personality disorders: a bibliometric analysis.Frontiers in psychiatry · 2026Pooled it
- Emotion Regulation Differences Between Gender and Sexuality Groups: A Systematic Review and Meta-Analysis.Archives of sexual behavior · 2025Pooled it
- The effects of childhood adversity: Two specific neural patterns.Neuroscience and biobehavioral reviews · 2025Pooled it
- The Efficacy of Experiential Dynamic Therapies: A 10-Year Systematic Review and Meta-Analysis Update.Clinical psychology & psychotherapyPooled it
- Personalized Mobile Health-Enhanced Cognitive Behavioral Intervention for Maternal Distress: Examining the Moderating Role of Adverse Childhood Experiences.The Permanente journal · 2024Trial
- Exploring the shared genetic architecture and causal relationship between childhood maltreatment and psychiatric disorders.Molecular psychiatry · 2026Article
- Emotion regulation and social information processing as targets of a guided selective prevention app for emerging adults with a history of adverse childhood experiences: A randomised controlled trial.Internet interventions · 2026Article
- Distinct Associations of Threat and Deprivation With Changes in Affective Control during Adolescence: A Longitudinal Population-Based Study.Developmental science · 2026Article
- Profiles of Adversity Across Family, Peer, and School: Predicting Depressive and Externalizing Symptoms Through Belief in a Just World Among Chinese Adolescents.Child psychiatry and human development · 2026Article
- Mapping links between childhood maltreatment and biopsychosocial health in pregnancy: a network analysis.Archives of women's mental health · 2026Article
- Self-Assessment of Social-Emotional Skills in Primary Students: Psychometric Evaluation of the Digital Screening Instrument GraSEF.Child psychiatry and human development · 2026Article
- Exploring the mediating role of functional connectivity in the association between violence exposure and psychopathology during early adolescence.Brain and cognition · 2026Article
- Differential adolescent neurodevelopment of emotion processing across internalizing psychopathology and childhood adversity.Developmental cognitive neuroscience · 2026Article
- Structural equation modeling of the effect of childhood trauma on premenstrual syndrome: the mediating role of rumination in adolescent girls.Scientific reports · 2026Article
- Emotion correction for weibo users via weakly supervised learning and semantic understanding.iScience · 2026Article
- Psychological and behavioral mechanisms linking childhood trauma profiles to voice-related distress in schizophrenia spectrum disorders: latent class, mediation, and conditional process analyses.Psychological medicine · 2026Article
- Emotion Regulation Mediates the Link Between Exposure to Childhood Adversity and Transdiagnostic Symptom Domains in Youth.JAACAP open · 2026Article
- Relationship between childhood adversity and premenstrual syndrome: mediating role of alexithymia and psychological distress in medical students.BMC women's health · 2026Article
21 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
Childhood adversity is a major risk factor for multiple forms of psychopathology, and recent efforts have focused on understanding the underlying psychological mechanisms. One outstanding candidate is emotion regulation, which has been associated with both childhood adversity, and psychopathology. Based on the available evidence, the present meta-analysis set out to investigate the mechanistic involvement of emotion regulation in the relation between childhood adversity and psychopathology. Systematic searches in three databases (PubMed; PsycINFO; Web of Science) identified 215 eligible studies. Using meta-analytic structural equation modeling, we fitted a partial mediation model to the available data across studies, in which childhood adversity was related to psychopathology both directly and through emotion regulation. Multiple emotion regulation dimensions were analyzed, including emotion regulation difficulties and the habitual use of rumination, distraction, reappraisal, and suppression. Measures of psychopathology included a wide range of internalizing and externalizing symptoms in both clinical and non-clinical samples. The results indicated that childhood adversity was positively associated with emotion regulation difficulties, as well as with the habitual use of rumination and suppression. In turn, these measures of emotion regulation were positively associated with psychopathology. Habitual reappraisal use showed negative relations with both childhood adversity and psychopathology. All these emotion regulation measures were supported as mediators in the relation between childhood adversity and psychopathology. In contrast, distraction was not related to childhood adversity or psychopathology, and its mediator role was not supported. These results suggest that altered emotion regulation is a consistent marker of childhood adversity and contributes to risk of psychopathology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.