Evidence map›Paper›PMID 35219855›Full record

ArticleNeurobiology of disease2022

Na

Carleigh Studtmann, Marek Ladislav, Mackenzie A Topolski, Mona Safari, Sharon A Swanger

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Dravet syndrome: novel insights intoFrontiers in neuroscience · 2025
    Review
  9. Voltage Gated Ion Channels and Sleep.The Journal of membrane biology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Heterozygous expression of abioRxiv : the preprint server for biology · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Carleigh StudtmannCenter for Neurobiology Research, Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA; Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA, USA.
Marek LadislavCenter for Neurobiology Research, Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA.
Mackenzie A TopolskiCenter for Neurobiology Research, Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA.
Mona SafariCenter for Neurobiology Research, Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA; Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA, USA.
Sharon A SwangerCenter for Neurobiology Research, Fralin Biomedical Research Institute at VTC, Virginia Tech, Roanoke, VA, USA; Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, USA; Department of Internal Medicine, Virginia Tech Carilion School of Medicine, Roanoke, VA, USA. Electronic address: saswanger@vtc.vt.edu.
Biomedical Research Institute · USCarilion Clinic · USVirginia Tech · US

Funding

Molecular and functional diversity of NMDA receptors in the thalamusR01NS105804 · NINDS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SWANGER, SHARON ANN · 2019 to 2023
$1.7M
NINDS NIH HHS R01 NS105804
6 · The paper itself

Abstract

Thalamocortical network dysfunction contributes to seizures and sleep deficits in Dravet syndrome (DS), an infantile epileptic encephalopathy, but the underlying molecular and cellular mechanisms remain elusive. DS is primarily caused by mutations in the SCN1A gene encoding the voltage-gated sodium channel Na

Indexed as

Epilepsies, MyoclonicGABAergic NeuronsAnimalsDisease Models, AnimalFemaleHaploinsufficiencyMaleMiceNAV1.1 Voltage-Gated Sodium ChannelThalamusNAV1.1 Voltage-Gated Sodium ChannelScn1a protein, mouseDravet syndromeExcitabilityGABAergicGlutamatergicNa(V)1.1Reticular thalamusSCN1ASomatosensory thalamusSynaptic transmissionThalamocortical neuron

Identifiers

PMID35219855
PMCPMC8957548
OpenAlexW4214740652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.