ReviewThe lancet. HIV2022
Delayed presentation of HIV among older individuals: a growing problem.
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Review in The lancet. HIV, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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59citing papers in PubMed
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Who cites it
59 citing papers in PubMed.
- Global burden of disease attributable to unsafe sex among adults aged 60 years and older, 1990-2023: a secondary analysis of the global burden of disease study 2023.Annals of medicine · 2026Article
- Documenting HIV service delivery and adoption of evidence-based practices in HIV care programs: A protocol for a cross-sectional survey of HIV clinics participating in the International epidemiology Databases to Evaluate AIDS (IeDEA).medRxiv : the preprint server for health sciences · 2026Article
- Identifying factors influencing HIV testing behavior among high-risk elderly men: a mixed-methods study incorporating structural equation modeling and thematic framework.BMC infectious diseases · 2026Article
- Characteristics of late HIV diagnosis in Germany in 2019 and 2020 - A regional analysis.Infection · 2026Article
- The Intersectionality of Stigma Toward HIV, Aging, Mental Illness, and Dementia Among Healthcare Professionals Serving the HIV-Infected Aging Population in Vietnam.AIDS and behavior · 2026Article
- New HIV diagnoses and risk factors for late HIV diagnosis, Finland, 2008-2023.Epidemiology and infection · 2026Article
- Trends in incidence and DALYs of infectious disease from 2000 to 2023 and the attributable risk factors in China: an analysis of the Global Burden of Disease Study 2023.The Lancet regional health. Western Pacific · 2026Article
- Current perspectives and emerging directions in research and practice: highlights from the 15th Annual International Workshop on Aging and HIV.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Qualitatively exploring opportunities and challenges for sexually transmitted infection prevention aimed at Canadian international retirement migrants wintering in the United States.BMC public health · 2026Article
- Determinants of immune recovery and survival in HIV late presenters: a retrospective cohort study from Southwest China.AIDS research and therapy · 2026Article
- Expert consensus on the clinical management of HIV late presentation.Infectious diseases & immunity · 2026Article
- A Case-Control Study of Virologic Failure Among People Living with HIV Enrolled in a NYC-Based Medicaid Special Needs Plan.AIDS and behavior · 2026Article
- Risk factors for late HIV diagnosis in England, 2015-2023.HIV medicine · 2026Article
- Annual trends and risk factors of late presentation of HIV at 19 referral hospitals in Indonesia: findings from the INA-PROACTIVE cohort.The Lancet regional health. Southeast Asia · 2026Article
- Beyond Neighbors: Social Capital and Self-Empowerment Among Older Adults Diagnosed with HIV Late.AIDS and behavior · 2026Article
- Declining prevalence of AIDS-defining illness among newly diagnosed people living with HIV in northern Thailand: a 10-year review.BMC infectious diseases · 2026Article
- Factors influencing late HIV presentation in China: results from logistic regression and Bayesian network analyses.BMC infectious diseases · 2026Article
- Molecular transmission network analysis of HIV-1 among older adults in Central China: a cross-sectional study in Shaodong City.Frontiers in microbiology · 2026Article
- Pathological Proliferation of CD4Infection and drug resistance · 2026Article
- Long-term evolution of the burden of HIV/AIDS in older adults: a global burden of disease analysis in individuals aged ≥75 years in G7 countries.Frontiers in public health · 2026Article
Corrections and comments
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Authors and funding
18 authors.
Amy C JusticeVA Connecticut Healthcare System, Yale Schools of Medicine and Public Health, Yale University, West Haven, CT, USA. Electronic address: amy.justice2@va.gov.
Matthew B GoetzVA Greater Los Angeles Healthcare System, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA.
Cameron N StewartDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Brenna C HoganDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Elizabeth HumesDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Paula M LuzAffiliation Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Jessica L CastilhoDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Denis NashCity University of New York Department of Epidemiology and Biostatistics, Graduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.
Ellen BrazierInstitute for Implementation Science in Population Health, Graduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.
Beverly MusickDepartment of Biostatistics and Health Data Science, School of Medicine, Indiana University, Indianapolis, IN, USA.
Constantin YiannoutsosDepartment of Biostatistics, Richard M Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.
Karen MalatesteInserm, French National Research Institute for Sustainable Development, Universite de Bordeaux, Bordeaux, France.
Antoine JaquetInserm, French National Research Institute for Sustainable Development, Universite de Bordeaux, Bordeaux, France.
Morna CornellCentre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Tinei ShamuGraduate School of Health Sciences, Institute of Social and Preventative Medicine, University of Bern, Bern, Switzerland.
Reena RajasuriarDepartment of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Awachana JiamsakulBiostatistics and Databases Program, The Kirby Institute, UNSW, Sydney, NSW, Australia.
Keri N AlthoffDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Funding
North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2MEast Africa International Epidemiology Database to evaluate AIDS (IeDEA) Regional ConsortiumU01AI069911 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI Leslie Anne Enane, AGGREY SEMWENDERO SEMEERE · 2006 to 2026
$57.7MObservational Antiretroviral Studies In Southern Africa (OASIS) CollaborationU01AI069924 · NIAID · UNIVERSITAT BERN · PI Cleophas Chimbetete, Mary-Ann Davies · 2006 to 2026
$55.9MThe Asia-Pacific HIV Research CollaborationU01AI069907 · NIAID · FOUNDATION FOR AIDS RESEARCH · PI ANNETTE H SOHN · 2006 to 2026
$44.8MCCASAnet: Caribbean, Central and South America NetworkU01AI069923 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Pedro Enrique Cahn, Jessica L Castilho · 2006 to 2026
$41.6M"Enhancing Cancer Research in Central Africa IeDEA"U01AI096299 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Denis Nash, Marcel Yotebieng · 2011 to 2026
$35.8MWADA (West Africa Database on Antiretroviral Therapy) CollaborationU01AI069919 · NIAID · UNIVERSITY OF BORDEAUX II · PI Didier Koumavi Ekouevi, Antoine Jaquet · 2006 to 2026
$29.9MAlcohol Associated Outcomes Among HIV+/- Aging VeteransU10AA013566 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2006 to 2010
$12.7MHarmonist: A Scalable Toolkit for Standardizing and Coordinating Data Sharing Across International Research NetworksR24AI124872 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Stephany Norah Duda · 2016 to 2026
$12.5MNeuro HPA Project 1U54AG062334 · NIA · EMORY UNIVERSITY · PI Ighovwerha Ofotokun · 2018 to 2026
$12.2MAlcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7MThe HIV and Alcohol Research center focused on Polypharmacy (HARP)P01AA029545 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2021 to 2025
$6.3MNIAAA NIH HHS P01 AA029545NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01 AA026224NIAAA NIH HHS U10 AA013566NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24 AA022001NIAID NIH HHS K23 AI120875NIAID NIH HHS R24 AI124872NIAID NIH HHS U01 AI069907NIAID NIH HHS U01 AI069911NIAID NIH HHS U01 AI069918NIAID NIH HHS U01 AI069919NIAID NIH HHS U01 AI069923NIAID NIH HHS U01 AI069924NIAID NIH HHS U01 AI096299NIA NIH HHS U54 AG062334
Abstract
Late presentation for care is a major impediment to the prevention and effective treatment of HIV infection. Older individuals are at increased risk of late presentation, represent a growing proportion of people with late presentation, and might require interventions tailored to their age group. We provide a summary of the literature published globally between 2016-21 (reporting data from 1984-2018) and quantify the association of age with delayed presentation. Using the most common definitions of late presentation and older age from these earlier studies, we update this work with data from the International Epidemiology Databases to Evaluate AIDS (IeDEA) consortium, focusing on data from 2000-19, encompassing four continents. Finally, we consider how late presentation among older individuals might be more effectively addressed as electronic medical records become widely adopted.
Indexed as
HIV InfectionsCD4 Lymphocyte CountDelayed DiagnosisHumansRisk Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.