Evidence map›Paper›PMID 35218474›Full record

ArticleJournal of fluorescence2022

Utilizing Experiment and Theory to Evaluate Rhodamine B ethylenediamine as a Fluorescent Sensor for G-type Nerve Agents.

Anna Hamstra, Yajie Cai, Zachary Reynolds, Cody S Griffins, Arnold L Rheingold, Nicholas J Schaaf, Ekkehard Sinn, Jefferson E Bates, Aruna J Weerasinghe

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of fluorescence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Anna HamstraDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA.
Yajie CaiDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA.
Zachary ReynoldsDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA.
Cody S GriffinsDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA.
Arnold L RheingoldDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, 92093, USA.
Nicholas J SchaafDepartment of Chemistry, East Carolina University, Greenville, NC, 27858, USA.
Ekkehard SinnDepartment of Chemistry, Western Michigan University, Kalamazoo, MI, 49008, USA.
Jefferson E BatesDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA. batesje@appstate.edu.
Aruna J WeerasingheDepartment of Chemistry and Fermentation Sciences, Appalachian State University, Boone, NC, 28608, USA. weerasingheag@appstate.edu.ORCID http://orcid.org/0000-0001-9797-9697
Appalachian State University · USEast Carolina University · USUniversity of California San Diego · USWestern Michigan University · US

Funding

Appalachian State University URC No:228806
6 · The paper itself

Abstract

Nerve gas mimic binding with Rhodamine B ethylenediamine (1) was studied in organic media. Binding of the nerve gas mimic, diethyl chlorophosphate (DCP), with the probe generated a non-fluorescent intermediate and a fluorescent product. Fluorescent and non-fluorescent products generated were identified using mass spectrometry and X-ray crystallography. Time-dependent density functional theory calculations were also used to investigate the electronic structure of the fluorescent probe in the ground and lowest lying π → π* singlet excited state. Though good agreement between theory and experiment can be obtained for the intense peak in the experimental spectrum using non-hybrid functionals, care must be taken when modelling these complexes due to the appearance of an n → π* transition that is too low in energy and appears to fall in the shoulders of the π → π* transitions.

Indexed as

Nerve AgentsEthylenediaminesFluorescent DyesRhodaminesEthylenediaminesFluorescent DyesNerve Agentsrhodamine BRhodaminesComputationalFluorescenceNerve AgentsRhodamineSensor

Identifiers

PMID35218474
OpenAlexW4214762694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.