ArticleJournal of mathematical biology2022
Classification of infinitesimal homeostasis in four-node input-output networks.
Article in Journal of mathematical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Homeostasis in networks with multiple inputs.Journal of mathematical biology · 2024Article
- Advancing physiology education by understanding the multiple dimensions of homeostasis.Frontiers in physiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
An input-output network has an input node [Formula: see text], an output node o, and regulatory nodes [Formula: see text]. Such a network is a core network if each [Formula: see text] is downstream from [Formula: see text] and upstream from o. Wang et al. (J Math Biol 82:62, 2021. https://doi.org/10.1007/s00285-021-01614-1 ) show that infinitesimal homeostasis can be classified in biochemical networks through infinitesimal homeostasis in core subnetworks. Golubitsky and Wang (J Math Biol 10:1-23, 2020) show that there are three types of 3-node core networks and three types of infinitesimal homeostasis in 3-node core networks. This paper uses the theory developed in Wang et al. (2021) to show that there are twenty types of 4-node core networks (Theorem 1.3) and seventeen types of infinitesimal homeostasis in 4-node core networks (Theorem 1.7). Biological contexts illustrate the classification theorems and show that the theory can be an aid when calculating homeostasis in specific biochemical networks.
Indexed as
Identifiers
35218429What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.