Evidence map›Paper›PMID 35218169›Full record

ReviewJournal of biomedical optics2022

Deep learning in macroscopic diffuse optical imaging.

Jason T Smith, Marien Ochoa, Denzel Faulkner, Grant Haskins, Xavier Intes

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 39 citations in OpenAlex.

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  14. Research square · 2023
    Article
  15. Article
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  18. Deep learning in fNIRS: a review.Neurophotonics · 2022
    Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jason T SmithRensselaer Polytechnic Institute, Department of Biomedical Engineering, Troy, New York, United States.
Marien OchoaRensselaer Polytechnic Institute, Department of Biomedical Engineering, Troy, New York, United States.
Denzel FaulknerRensselaer Polytechnic Institute, Department of Biomedical Engineering, Troy, New York, United States.
Grant HaskinsRensselaer Polytechnic Institute, Department of Biomedical Engineering, Troy, New York, United States.
Xavier IntesRensselaer Polytechnic Institute, Center for Modeling, Simulation and Imaging for Medicine, Troy, Ne, United States.
Rensselaer Polytechnic Institute · US

Funding

Role of tumor heterogeneity on receptor engagementR01CA207725 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, CORR, DAVID THOMAS · 2017 to 2021
$3.0M
In vivo Macroscopic Fluorescence Lifetime Molecular Optical ImagingR01CA250636 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2020 to 2023
$2.9M
Photon-counting X-ray and Optical Tomography for Preclinical Cancer ResearchR01CA237267 · NCI · RENSSELAER POLYTECHNIC INSTITUTE · PI BARROSO, MARGARIDA, INTES, XAVIER · 2019 to 2023
$2.9M
NCI NIH HHS R01 CA207725NCI NIH HHS R01 CA237267NCI NIH HHS R01 CA250636
6 · The paper itself

Abstract

significanceBiomedical optics system design, image formation, and image analysis have primarily been guided by classical physical modeling and signal processing methodologies. Recently, however, deep learning (DL) has become a major paradigm in computational modeling and has demonstrated utility in numerous scientific domains and various forms of data analysis.

aimWe aim to comprehensively review the use of DL applied to macroscopic diffuse optical imaging (DOI). APPROACH: First, we provide a layman introduction to DL. Then, the review summarizes current DL work in some of the most active areas of this field, including optical properties retrieval, fluorescence lifetime imaging, and diffuse optical tomography.

resultsThe advantages of using DL for DOI versus conventional inverse solvers cited in the literature reviewed herein are numerous. These include, among others, a decrease in analysis time (often by many orders of magnitude), increased quantitative reconstruction quality, robustness to noise, and the unique capability to learn complex end-to-end relationships.

conclusionsThe heavily validated capability of DL's use across a wide range of complex inverse solving methodologies has enormous potential to bring novel DOI modalities, otherwise deemed impractical for clinical translation, to the patient's bedside.

Indexed as

Deep LearningTomography, OpticalComputer SimulationHumansImage Processing, Computer-AssistedSpectrum Analysisdeep learningdiffuse optical tomographydiffuse opticsfluorescence molecular tomographylifetime imagingmacroscopic diffuse opticsreviewtissue hemodynamics

Identifiers

PMID35218169
PMCPMC8881080
OpenAlexW4214667422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.