Evidence map›Paper›PMID 35218128›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2022

Whole-exome sequencing uncovers new variants in GDF15 associated with hyperemesis gravidarum.

Marlena S Fejzo, Kimber W MacGibbon, Olivia First, Courtney Quan, Patrick M Mullin

Abstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  10. Sensory signals for nausea.Trends in neurosciences · 2025
    Review
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  17. GDF15 Targeting for Treatment of Hyperemesis Gravidarum.Medicines (Basel, Switzerland) · 2024
    Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Marlena S FejzoDepartment of Maternal Fetal Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-6800-687X
Kimber W MacGibbonHyperemesis Education and Research Foundation, Clackamas, Oregon, USA.
Olivia FirstHyperemesis Education and Research Foundation, Clackamas, Oregon, USA.
Courtney QuanHyperemesis Education and Research Foundation, Clackamas, Oregon, USA.
Patrick M MullinDepartment of Maternal Fetal Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Growth Differentiation Factor 15Hyperemesis GravidarumExome SequencingFemaleHumansNauseaPregnancyGDF15 protein, humanGrowth Differentiation Factor 15appetiteGDF15hyperemesis gravidarumnauseavomitingwhole-exome sequencing

Identifiers

PMID35218128
PMCPMC9546032

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.