ArticleClinical drug investigation2022
The Impact of COVID-19 Vaccination on the Italian Healthcare System: A Scenario Analysis.
Article in Clinical drug investigation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The COVID-19 Pandemic and Health and Care Workers: Findings From a Systematic Review and Meta-Analysis (2020-2021).International journal of public health · 2023Pooled it
- Evaluating the utilisation patterns of pharmacological therapy in COVID-19 patients: an ecological study in Italy.BMJ public health · 2025Article
- Personality Traits and Sociodemographic Variables' Effects on Parental Burnout During the Second and Fourth COVID-19 Waves in Italian Parents.International journal of environmental research and public health · 2024Article
- A Comprehensive Review on the Intricate Interplay between COVID-19 Immunization and the New Onset of Pemphigus Foliaceus.Vaccines · 2024Review
- Neurovascular Adverse Effects of Sars-Cov-2 Vaccination.Drug design, development and therapy · 2024Review
- Predictive potential of SARS-CoV-2 RNA concentration in wastewater to assess the dynamics of COVID-19 clinical outcomes and infections.The Science of the total environment · 2023Article
- A population-based assessment of avoidable hospitalizations and resource use of non-vaccinated patients with COVID-19.Canadian journal of public health = Revue canadienne de sante publique · 2023Article
- The Impact of Vaccination on COVID-19 Burden of Disease in the Adult and Elderly Population: A Systematic Review of Italian Evidence.Vaccines · 2023Review
- Management of the Medico-Legal Dispute of Healthcare-Related SARS-CoV-2 Infections: Evaluation Criteria and Case Study in a Large University Hospital in Northwest Italy from 2020 to 2021.International journal of environmental research and public health · 2022Article
- Who complies with prevention guidelines during the fourth wave of COVID-19 in Italy? An empirical study.Personality and individual differences · 2022Article
- Narrative Review of the COVID-19 Pandemic's First Two Years in Italy.International journal of environmental research and public health · 2022Review
- Avoidable intensive care unit resource use and costs of unvaccinated patients with COVID-19: a historical population-based cohort study.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2022Article
- Autoimmune mucocutaneous blistering diseases after SARS-Cov-2 vaccination: A Case report of Pemphigus Vulgaris and a literature review.Pathology, research and practice · 2022Review
- COVID-19 hospitalizations and patients' age at admission: The neglected importance of data variability for containment policies.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectiveDuring 2020, the only instruments for fighting against the pandemic peaks were lockdowns, physical distancing, closure of schools and non-essential businesses, and travel restrictions. The new vaccination strategy adopted in Italy in 2021 represented a new perspective for policymakers.
objectiveThe aim of this study was to estimate the effects of the national immunisation strategy for coronavirus disease 2019 (COVID-19) in Italy on the national healthcare system.
methodsAn epidemiological scenario analysis was developed in order to simulate the impact of the COVID-19 pandemic on the Italian national healthcare system in 2021. Hospitalisations, intensive care unit (ICU) admissions and death rates were modelled based on 2020 data. Costs were estimated using hospital admissions from the Policlinico of Tor Vergata Hospital in Rome. Two scenarios were tested, one with vaccination and the second without.
resultsThe roll-out of vaccinations to protect against COVID-19 was estimated to prevent 52,115 deaths in 2021, 45.2% less than what was expected in the absence of immunisation. Based on the assumptions underlying the two epidemiological scenarios, our model predicted an overall reduction of 2.4 million hospital admissions and 259,000 ICU admissions (74.9% and 71.3% less, respectively, than the world without vaccinations between June and December 2021). Overall, in Italy, the model estimated over €3.0 billion costs of hospitalisations due to COVID-19 in 2020. In 2021, vaccines prevented around 36% of the overall costs.
conclusionsThis is the first study highlighting the effect of vaccines on the Italian healthcare system in terms of avoided cases, hospitalisations and costs. Our results have the potential to inform policymakers and the general population on the benefits of vaccinations.
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