Evidence map›Paper›PMID 35217605›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

BIN1 modulation in vivo rescues dynamin-related myopathy.

Valentina Maria Lionello, Christine Kretz, Evelina Edelweiss, Corinne Crucifix, Raquel Gómez-Oca, Nadia Messaddeq, Suzie Buono, Pascale Koebel, Xènia Massana Muñoz, Nadège Diedhiou and 3 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Gene replacement therapy for centronuclear myopathy: A breakthrough in complex genetic muscle disease.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  6. BIN1 reduction amelioratesProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. [Association between serum BIN1 level and Killip class in patients with acute myocardial infraction].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  8. Review
  9. Article
  10. Dynamics of membrane tubulation coupled with fission by a two-component module.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Valentina Maria LionelloInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.ORCID 0000-0002-5737-6821
Christine KretzInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Evelina EdelweissInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Corinne CrucifixInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Raquel Gómez-OcaInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.ORCID 0000-0001-8778-4175
Nadia MessaddeqInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.ORCID 0000-0001-8398-6415
Suzie BuonoInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.ORCID 0000-0001-5694-2249
Pascale KoebelInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.ORCID 0000-0002-7574-1300
Xènia Massana MuñozInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Nadège DiedhiouInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Belinda S CowlingInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France.
Marc BitounInstitute of Myology, Centre of Research in Myology, INSERM, UMRS 974, Sorbonne Université, F-75013, Paris, France.
Jocelyn LaporteInstitut de Génétique et de Biologie Moléculaire et Cellulaire, INSERM U1258, CNRS UMR 7104, Université de Strasbourg, Illkirch, F-67404, France; jocelyn@igbmc.fr.ORCID 0000-0001-8256-5862
Centre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanoenzyme dynamin 2 (DNM2) is crucial for intracellular organization and trafficking.

Indexed as

Adaptor Proteins, Signal TransducingAnimalsDynamin IIHumansMiceMice, KnockoutMuscular AtrophyMuscular DiseasesNuclear ProteinsProtein BindingTumor Suppressor ProteinsAdaptor Proteins, Signal TransducingBIN1 protein, humanDNM2 protein, humanDynamin IINuclear ProteinsTumor Suppressor Proteinsamphiphysincongenital myopathydynamingene therapymembrane remodeling

Identifiers

PMID35217605
PMCPMC8892365
OpenAlexW4214748758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.