Evidence map›Paper›PMID 35217548›Full record

ArticleBMJ case reports2022

Visual loss and optic neuropathy in a patient with Klinefelter's syndrome, open-angle glaucoma, vitamin B

Jyotin C Pandit, Thomas William McNally, Hani Hasan, Rachel Leanna Pandit

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jyotin C PanditEye Department, Great Western Hospital, Swindon, UK j.pandit@nhs.net.
Thomas William McNallyMoorfields Eye Department, St George's Hospital, London, UK.ORCID http://orcid.org/0000-0003-2893-5708
Hani HasanEye Department, Great Western Hospital, Swindon, UK.
Rachel Leanna PanditMoor Eye Care, Marlborough, UK.
Great Western Hospital · GBMoorfields Eye Hospital · GBSt George's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old man with Klinefelter's syndrome presented to the neuro-ophthalmology clinic with progressive painless visual blurring in the right eye over 2 years. He was receiving intramuscular testosterone therapy for hypogonadism and hypromellose for dry eye. Acuity was reduced bilaterally, and the right optic nerve head appeared pale and asymmetrically cupped. Optical coherence tomography revealed loss of retinal nerve fibre layer thickness in the right eye and visual field testing showed a developing right-ring scotoma. Blood tests showed vitamin B

Indexed as

Glaucoma, Open-AngleKlinefelter SyndromeOptic Nerve DiseasesFolic AcidHumansIntraocular PressureMaleMiddle AgedTomography, Optical CoherenceVitamin B 12VitaminsFolic AcidVitamin B 12Vitaminsendocrinologygeneticsglaucomaretinavitamins and supplements

Identifiers

PMID35217548
PMCPMC8883182
OpenAlexW4214660751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.