Evidence map›Paper›PMID 35217544›Full record

ArticleeNeuro

Linking Brain Structure, Activity, and Cognitive Function through Computation.

Katrin Amunts, Javier DeFelipe, Cyriel Pennartz, Alain Destexhe, Michele Migliore, Philippe Ryvlin, Steve Furber, Alois Knoll, Lise Bitsch, Jan G Bjaalie and 5 more

Abstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Katrin AmuntsInstitute of Neurosciences and Medicine (INM-1), Research Centre Jülich, Jülich 52425, Germany k.amunts@fz-juelich.de.
Javier DeFelipeLaboratorio Cajal de Circuitos Corticales, Centro de Tecnología Biomédica, Universidad Politécnica de Madrid, Madrid 28223, Spain.ORCID 0000-0001-5484-0660
Cyriel PennartzCognitive and Systems Neuroscience Group, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, 1098 XH, The Netherlands.ORCID 0000-0001-8328-1175
Alain DestexheCentre National de la Recherche Scientifique, Institute of Neuroscience (NeuroPSI), Paris-Saclay University, Gif sur Yvette 91400, France.ORCID 0000-0001-7405-0455
Michele MiglioreInstitute of Biophysics, National Research Council, Palermo 90146, Italy.
Philippe RyvlinDepartment of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Lausanne CH-1011, Switzerland.
Steve FurberDepartment of Computer Science, The University of Manchester, Manchester M13 9PL, United Kingdom.
Alois KnollDepartment of Informatics, Technical University of Munich, Garching 385748, Germany.
Lise BitschThe Danish Board of Technology Foundation, Copenhagen, 2650 Hvidovre, Denmark.
Jan G BjaalieInstitute of Basic Medical Sciences, University of Oslo, Oslo, Norway.
Yannis IoannidisATHENA Research & Innovation Center, Athena 12125, Greece.
Thomas LippertInstitute for Advanced Simulation (IAS), Jülich Supercomputing Centre (JSC), Research Centre Jülich, Jülich 52425, Germany.
Maria V Sanchez-VivesICREA and Systems Neuroscience, Institute of Biomedical Investigations August Pi i Sunyer, Barcelona 08036, Spain.ORCID 0000-0002-8437-9083
Rainer GoebelDepartment of Cognitive Neuroscience, Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, Maastricht 6229 EV, The Netherlands.
Viktor JirsaAix Marseille Université, Institut National de la Santé et de la Recherche Médicale, Institut de Neurosciences des Systèmes (INS) UMR1106, Marseille 13005, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Understanding the human brain is a "Grand Challenge" for 21st century research. Computational approaches enable large and complex datasets to be addressed efficiently, supported by artificial neural networks, modeling and simulation. Dynamic generative multiscale models, which enable the investigation of causation across scales and are guided by principles and theories of brain function, are instrumental for linking brain structure and function. An example of a resource enabling such an integrated approach to neuroscientific discovery is the BigBrain, which spatially anchors tissue models and data across different scales and ensures that multiscale models are supported by the data, making the bridge to both basic neuroscience and medicine. Research at the intersection of neuroscience, computing and robotics has the potential to advance neuro-inspired technologies by taking advantage of a growing body of insights into perception, plasticity and learning. To render data, tools and methods, theories, basic principles and concepts interoperable, the Human Brain Project (HBP) has launched EBRAINS, a digital neuroscience research infrastructure, which brings together a transdisciplinary community of researchers united by the quest to understand the brain, with fascinating insights and perspectives for societal benefits.

Indexed as

NeurosciencesRoboticsBrainCognitionHumansNeural Networks, Computerartificial neuronal networksbrain complexityconnectivityhuman brain mappingmultiscale brain organizationneuro-inspired technology

Identifiers

PMID35217544
PMCPMC8925650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.