Evidence map›Paper›PMID 35217299›Full record

ArticleDevelopmental cognitive neuroscience2022

Early experience unpredictability in child development as a model for understanding the impact of the COVID-19 pandemic: A translational neuroscience perspective.

Sihong Liu, Philip A Fisher

Open access · goldAbstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Research Review: Assessment of early-life adversity and trauma - cumulative risk and dimensional approaches.Journal of child psychology and psychiatry, and allied disciplines · 2025
    Review
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  7. Prenatal Stress and Maternal Role in Neurodevelopment.Annual review of developmental psychology · 2024
    Article
  8. Review
  9. Article
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  11. The role of childhood unpredictability in adult health.Journal of behavioral medicine · 2023
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Sihong LiuCenter for Translational Neuroscience, Department of Psychology, University of Oregon, Eugene, OR, United States. Electronic address: sihongl@uoregon.edu.
Philip A FisherCenter for Translational Neuroscience, Department of Psychology, University of Oregon, Eugene, OR, United States.
University of Oregon · US

Funding

Supplement to Prevention Research Center: Parenting Among Women Who Are Opioid Users, Project 2P50DA048756 · NIDA · UNIVERSITY OF OREGON · PI BERKMAN, ELLIOT TODD · 2019 to 2023
$18.0M
NIDA NIH HHS P50 DA048756
6 · The paper itself

Abstract

Extensive evidence links adverse experiences during childhood to a wide range of negative consequences in biological, socioemotional, and cognitive development. Unpredictability is a core element underlying most forms of early adversity; it has been a focus of developmental research for many years and has been receiving increasing attention recently. In this article, we propose a conceptual model to describe how unpredictable and adverse early experiences affect children's neurobiological, behavioral, and psychological development in the context of the COVID-19 pandemic. We first highlight the critical role of unpredictability in child development by reviewing existing conceptual models of early adversity as they relate to subsequent development across the lifespan. Then, we employ a translational neuroscience framework to summarize the current animal- and human-based evidence on the neurobiological alterations induced by early experience unpredictability. We further argue that the COVID-19 pandemic serves as a global "natural experiment" that provides rare insight to the investigation of the negative developmental consequences of widespread, clustered, and unpredictable adverse events among children. We discuss how the pandemic helps advance the science of unpredictable early adverse experiences. As unpredictability research continues to grow, we highlight several directions for future studies and implications for policymaking and intervention practices.

Indexed as

COVID-19NeurosciencesChild DevelopmentHumansNeurobiologyPandemicsCOVID-19 PandemicEarly AdversityInstabilityTranslational NeuroscienceUnpredictability

Identifiers

PMID35217299
PMCPMC8860470
OpenAlexW4213178821

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.