Evidence map›Paper›PMID 35217130›Full record

ArticleThe Journal of hospital infection2022

Diagnostic accuracy of the Abbott ID NOW SARS-CoV-2 rapid test for the triage of acute medical admissions.

J R Barnacle, H Houston, I Baltas, J Takata, K Kavallieros, N Vaughan, A K Amin, S A Aali, K Moore, P Milner and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of hospital infection, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Review
  6. [Implementation of isotermic PCR for detection of SARS-CoV-2 virus].Revista medica del Instituto Mexicano del Seguro Social · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

J R BarnacleNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK. Electronic address: james.barnacle1@nhs.net.
H HoustonNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
I BaltasNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
J TakataNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
K KavallierosNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
N VaughanNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
A K AminNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
S A AaliNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
K MooreNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
P MilnerNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
A Gupta WrightInstitute for Global Health, University College London, London, UK; Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.
L JohnNorthwick Park Hospital, London North West University Healthcare NHS Trust, London, UK.
London North West Healthcare NHS Trust · GBUniversity of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDecisions to isolate patients at risk of having coronavirus disease 2019 (COVID-19) in the emergency department (ED) must be rapid and accurate to ensure prompt treatment and maintain patient flow whilst minimising nosocomial spread. Reverse transcription polymerase chain reaction (RT-PCR) assays are too slow to achieve this, and near-patient testing is being used increasingly to facilitate triage. The ID NOW severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) assay is an isothermal nucleic acid amplification near-patient test which targets the RNA-dependent RNA-polymerase gene.

aimTo assess the diagnostic performance of ID NOW as a COVID-19 triage tool for medical admissions from the ED of a large acute hospital.

methodsAll adult acute medical admissions from the ED between 31

findingsTwo percent (124/6050) of medical admissions were SARS-CoV-2 positive on RT-PCR. Compared with PCR, ID NOW had sensitivity and specificity of 83.1% [95% confidence interval (CI) 75.4-88.7] and 99.5% (95% CI 99.3-99.6), respectively. PPV and NPV were 76.9% (95% CI 69.0-83.2) and 99.6% (95% CI 99.5-99.8), respectively. The median time from arrival in the ED to ID NOW result was 59 min.

conclusionID NOW provides a rapid and reliable adjunct for the safe triage of patients with COVID-19, and can work effectively when integrated into an ED triage algorithm.

Indexed as

COVID-19SARS-CoV-2AdultCOVID-19 TestingHumansRNASensitivity and SpecificityTriageRNACOVID-19Emergency departmentID NOWNear-patient testingSARS-CoV-2Triage

Identifiers

PMID35217130
PMCPMC8863956
OpenAlexW4213196418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.