Evidence map›Paper›PMID 35216987›Full record

ArticleThe Annals of thoracic surgery2022

A Novel Device for Intraoperative Direct Visualization of a Pressurized Root in Aortic Valve Repair.

Yuanjia Zhu, Annabel M Imbrie-Moore, Michael J Paulsen, Matthew H Park, Nicholas A Tran, Y Joseph Woo

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Annals of thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuanjia ZhuDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California; Department of Bioengineering, Stanford University, Stanford, California.
Annabel M Imbrie-MooreDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California; Department of Mechanical Engineering, Stanford University, Stanford, California.
Michael J PaulsenDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California.
Matthew H ParkDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California; Department of Mechanical Engineering, Stanford University, Stanford, California.
Nicholas A TranDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California.
Y Joseph WooDepartment of Cardiothoracic Surgery, Stanford University, Stanford, California; Department of Bioengineering, Stanford University, Stanford, California. Electronic address: joswoo@stanford.edu.
Stanford University · US

Funding

ANGIOGENIC TISSUE ENGINEERING TO LIMIT POST-INFARCTION VENTRICULAR REMODELINGR01HL089315 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI WOO, Y JOSEPH · 2008 to 2023
$6.4M
Biomechanical Optimization of Mitral Valve Repair OperationsR01HL152155 · NHLBI · STANFORD UNIVERSITY · PI WOO, Y JOSEPH · 2020 to 2025
$5.9M
NHLBI NIH HHS R01 HL089315NHLBI NIH HHS R01 HL152155
6 · The paper itself

Abstract

purposeOne major challenge in generating reproducible aortic valve (AV) repair results is the inability to assess AV morphology under physiologic pressure. A transparent intraoperative AV visualization device was designed and manufactured. DESCRIPTION: This device comprises an open proximal end, a cantilevered edge to allow attachment of the device to the aorta or graft, a distal viewing surface, and 2 side ports for fluid delivery and air removal. EVALUATION: The performance of the device was evaluated ex vivo using normal porcine AV in situ (n = 3), porcine AV after valve-sparing aortic root replacement (VSARR) (n = 3), porcine pulmonary valve in the Ross procedure (n = 3), and in 3 patients who underwent VSARR. AV morphology was clearly visualized using the device in all experiments. In human subjects, the use of this device successfully showed cusp prolapse after the initial VSARR and effectively guided additional cusp repair.

conclusionsThis device successfully allows for direct visual assessment of the AV apparatus under physiologic pressure. The use of this device can potentially increase the adoptability of AV repair in clinical practice.

Indexed as

Aortic Valve InsufficiencyCardiac Surgical ProceduresAnimalsAortaAortic ValveHumansSwineTreatment Outcome

Identifiers

PMID35216987
PMCPMC9393902
OpenAlexW4213055272

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.