Evidence map›Paper›PMID 35216939›Full record

ReviewJournal of geriatric oncology2022

Geriatric assessment in older adults with non-Hodgkin lymphoma: A Young International Society of Geriatric Oncology (YSIOG) review paper.

Othman Salim Akhtar, Li-Wen Huang, Mazie Tsang, Pallawi Torka, Kah Poh Loh, Vicki A Morrison, Raul Cordoba

Abstract readReview
In one paragraph

Review in Journal of geriatric oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. The performance of abbreviated comprehensive geriatric assessment in elderly patients with diffuse large B cell lymphoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. In pursuit of a functional cure for follicular lymphoma.Hematology. American Society of Hematology. Education Program · 2024
    Review
  8. Article
  9. Tailoring Therapy in Older Adults With Hematologic Malignancies.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2024
    Review
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Othman Salim AkhtarRoswell Park Comprehensive Cancer Center, Buffalo, NY, USA. Electronic address: othman.akhtar@roswellpark.org.
Li-Wen HuangSan Francisco VA Medical Center, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Mazie TsangHelen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.
Pallawi TorkaRoswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
Kah Poh LohUniversity of Rochester Medical Center, James P. Wilmot Cancer Institute, Rochester, NY, USA.
Vicki A MorrisonHennepin Healthcare/University of Minnesota, Minneapolis, MN, USA.
Raul CordobaFundacion Jimenez Diaz University Hospital, Health Research Institute IIS-FJD, Madrid, Spain.

Funding

RESEARCH TRAINING IN GERIATRIC MEDICINET32AG000212 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 1991 to 2026
$7.7M
A novel mobile health exercise intervention for older patients with myeloid neoplasmsR00CA237744 · NCI · UNIVERSITY OF ROCHESTER · PI LOH, KAH POH · 2021 to 2023
$747k
Cognitive trajectories and risk factors for cognitive decline in older adults with hematologic malignanciesR03AG067935 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI HUANG, LI-WEN · 2021 to 2022
$307k
NCI NIH HHS R00 CA237744NIA NIH HHS R03 AG067935NIA NIH HHS T32 AG000212
6 · The paper itself

Abstract

Non-Hodgkin lymphoma (NHL) is a disease of older adults, with a median age at diagnosis of 67 years. Treatment in older adults with NHL is challenging. The aging process is associated with a decline in functional reserve that varies among individuals, and results in an increasing risk of treatment-related toxicity and mortality. Chronological age and performance status fail to capture the multidimensional and heterogeneous nature of the aging process. A geriatric assessment (GA) screens multiple geriatric domains and provides a more accurate assessment of functional reserve. Several abbreviated GA tools have been developed for use in oncology clinics and help identify patients at high risk for chemotherapy-related toxicity and mortality. In this review, we explore GA tools validated for use in patients with NHL. We discuss the evidence behind GA-guided treatment in NHL and present a suggested approach to assessing frailty in this patient population.

Indexed as

FrailtyLymphoma, Non-HodgkinNeoplasmsAgedGeriatric AssessmentHumansFrailtyGeriatric assessmentLymphomaNon-Hodgkin lymphomaOlder adults

Identifiers

PMID35216939
PMCPMC9232919

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.