ArticleCell2022
Reconstruction of neocortex: Organelles, compartments, cells, circuits, and activity.
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Article in Cell, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.
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118citing papers in PubMed
20.1field-weighted citation impact, top 1% of its field
What it found
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Who cites it
118 citing papers in PubMed, 211 citations in OpenAlex.
- Mapping brain-wide monosynaptic inputs to single neurons with ROInet-seq.Cell reports methods · 2026Article
- Dendritic shaft constrictions shape synaptic integration in neurons.Science advances · 2026Article
- Hippocampal CA3 connectomics reveals a gradient of mossy fiber inputs and selective feedforward inhibition onto pyramidal cells.Nature neuroscience · 2026Article
- Brain mitochondria as key drivers of cognition and behaviour.Nature reviews. Neuroscience · 2026Review
- Approaching a connectome of the human foveal retina.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Highly energy-efficient information-handling dynamics of the brain.National science review · 2026Article
- Microglia extract neuronal proteolytic organelles via skoupocytosis.bioRxiv : the preprint server for biology · 2026Article
- Sleep reveals dynamics integrating and segregating movement and stimulus representations in V1.Nature communications · 2026Article
- Histologically Informed Multiscale Modeling of the Neuronal Elements Activated by TMS.bioRxiv : the preprint server for biology · 2026Article
- Physical contact reveals a hidden layer of cortical architecture.bioRxiv : the preprint server for biology · 2026Article
- Connectome-seq: high-throughput mapping of neuronal connectivity at single-synapse resolution via barcode sequencing.Nature methods · 2026Article
- Article
- Spatial and morphological organization of mitochondria in neurons across a connectome.Science (New York, N.Y.) · 2026Article
- Stretch and flow at the gliovascular interface: High-fidelity modeling of astrocyte endfeet.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Digging Deep into Alzheimer Disease: How Electron Microscopy Helps Elucidating Its Pathogenesis.Cellular and molecular neurobiology · 2026Review
- Convergent information flows explain recurring firing patterns in cerebral cortex.Nature neuroscience · 2026Article
- Ultrastructure of astrocytes using volume electron microscopy: A scoping review.The Journal of physiology · 2026Article
- Synaptic-resolution connectomics: towards large brains and connectomic screening.Nature reviews. Neuroscience · 2026Review
- Connectome of a human foveal retina.bioRxiv : the preprint server for biology · 2026Article
- Decoding gray matter, large-scale analysis of brain cell morphometry to inform microstructural modeling of diffusion MR signals.Communications biology · 2026Article
58 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
45 authors at 5 institutions in 1 country.
Nicholas L TurnerPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
Thomas MacrinaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
J Alexander BaePrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Electrical and Computer Engineering Department, Princeton University, Princeton, NJ 08544, USA.
Runzhe YangPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
Alyssa M WilsonPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Casey Schneider-MizellAllen Institute for Brain Science, Seattle, WA 98109, USA.
Kisuk LeePrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Brain & Cognitive Sciences Department, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Ran LuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Jingpeng WuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Agnes L BodorAllen Institute for Brain Science, Seattle, WA 98109, USA.
Adam A BleckertAllen Institute for Brain Science, Seattle, WA 98109, USA.
Derrick BrittainAllen Institute for Brain Science, Seattle, WA 98109, USA.
Emmanouil FroudarakisDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA.
Sven DorkenwaldPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
Forrest CollmanAllen Institute for Brain Science, Seattle, WA 98109, USA.
Nico KemnitzPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Dodam IhPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
William M SilversmithPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Jonathan ZungPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
Aleksandar ZlateskiElectrical Engineering and Computer Science Department, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Ignacio TartavullPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Szi-Chieh YuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Sergiy PopovychPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA.
Shang MuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
William WongPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Chris S JordanPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
Manuel CastroPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA.
JoAnn BuchananAllen Institute for Brain Science, Seattle, WA 98109, USA.
Daniel J BumbargerAllen Institute for Brain Science, Seattle, WA 98109, USA.
Marc TakenoAllen Institute for Brain Science, Seattle, WA 98109, USA.
Russel TorresAllen Institute for Brain Science, Seattle, WA 98109, USA.
Gayathri MahalingamAllen Institute for Brain Science, Seattle, WA 98109, USA.
Leila ElabbadyAllen Institute for Brain Science, Seattle, WA 98109, USA.
Yang LiAllen Institute for Brain Science, Seattle, WA 98109, USA.
Erick CobosDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA.
Pengcheng ZhouDepartment of Statistics, Columbia University, New York, NY 10027, USA; Center for Theoretical Neuroscience, Columbia University, New York, NY 10027, USA; Grossman Center for the Statistics of Mind, Columbia University, New York, NY 10027, USA.
Shelby SuckowAllen Institute for Brain Science, Seattle, WA 98109, USA.
Lynne BeckerAllen Institute for Brain Science, Seattle, WA 98109, USA.
Liam PaninskiDepartment of Statistics, Columbia University, New York, NY 10027, USA; Center for Theoretical Neuroscience, Columbia University, New York, NY 10027, USA; Grossman Center for the Statistics of Mind, Columbia University, New York, NY 10027, USA; Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA; Department of Neuroscience, Columbia University, New York, NY 10027, USA; Kavli Institute for Brain Science at Columbia University, New York, NY 10027, USA.
Franck PolleuxZuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA; Department of Neuroscience, Columbia University, New York, NY 10027, USA; Kavli Institute for Brain Science at Columbia University, New York, NY 10027, USA.
Jacob ReimerDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA.
Andreas S ToliasDepartment of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA; Center for Neuroscience and Artificial Intelligence, Baylor College of Medicine, Houston, TX 77030, USA; Department of Electrical and Computer Engineering, Rice University, Houston, TX 77005, USA.
R Clay ReidAllen Institute for Brain Science, Seattle, WA 98109, USA.
Nuno Maçarico da CostaAllen Institute for Brain Science, Seattle, WA 98109, USA.
H Sebastian SeungPrinceton Neuroscience Institute, Princeton University, Princeton, NJ 08544, USA; Computer Science Department, Princeton University, Princeton, NJ 08544, USA. Electronic address: sseung@princeton.edu.
Princeton University · USAllen Institute for Brain Science · USBaylor College of Medicine · USColumbia University · USMassachusetts Institute of Technology · US
Funding
Subcortical Neural Coding and DynamicsU19NS104648 · NINDS · PRINCETON UNIVERSITY · PI WANG, SAMUEL SHENG-HUNG · 2017 to 2021
$15.3MCollaboratory for atlasing cell type anatomy in the female and male mouse brainU01MH114824 · NIMH · COLD SPRING HARBOR LABORATORY · PI MITRA, PARTHA PRATIM · 2017 to 2021
$11.7MNRSA Training Grant in Quantitative NeuroscienceT32MH065214 · NIMH · PRINCETON UNIVERSITY · PI Nathaniel Douglass Daw, KENNETH A NORMAN · 2002 to 2026
$7.9MCircuit Mechanisms Underlying Persistent Activity in a Neural IntegratorR01EY027036 · NEI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Emre R Aksay, MARK S GOLDMAN · 2016 to 2026
$6.4MStructure and Function of a Cubic Millimeter of Cortex: Crowdsourcing for Proofreading and DiscoveryRF1MH123400 · NIMH · PRINCETON UNIVERSITY · PI SEUNG, HYUNJUNE SEBASTIAN · 2020 to 2020
$6.4MCircuit Mechanisms Underlying Learned Changes in Persistent Neural ActivityR01NS104926 · NINDS · WEILL MEDICAL COLL OF CORNELL UNIV · PI AKSAY, EMRE R, GOLDMAN, MARK S · 2018 to 2022
$4.1MCrowdsourcing the Fly ConnectomeRF1MH117815 · NIMH · PRINCETON UNIVERSITY · PI MURTHY, MALA, SEUNG, HYUNJUNE SEBASTIAN · 2018 to 2018
$3.3MRole of ER-mitochondria contacts in dendritic Ca2+ homeostasis, synaptic integration and circuit functionR01NS107483 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI POLLEUX, FRANCK · 2019 to 2021
$1.6MNEI NIH HHS R01 EY027036NIMH NIH HHS RF1 MH117815NIMH NIH HHS RF1 MH123400NIMH NIH HHS T32 MH065214NIMH NIH HHS U01 MH114824NINDS NIH HHS R01 NS104926NINDS NIH HHS R01 NS107483NINDS NIH HHS U19 NS104648
Abstract
We assembled a semi-automated reconstruction of L2/3 mouse primary visual cortex from ∼250 × 140 × 90 μm
Indexed as
NeocortexAnimalsMiceMicroscopy, ElectronOrganellesPyramidal CellsSynapsesmouse, cortex, 3D reconstruction, electron microscopy, calcium imaging, pyramidal cell, mitochondria, synaptic connectivity, inhibitory cell, visual cortex
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.