Evidence map›Paper›PMID 35216531›Full record

ReviewAnnual review of analytical chemistry (Palo Alto, Calif.)2022

Overcoming Major Barriers to Developing Successful Sensors for Practical Applications Using Functional Nucleic Acids.

JingJing Zhang, Tian Lan, Yi Lu

Open access · greenAbstract readReview
In one paragraph

Review in Annual review of analytical chemistry (Palo Alto, Calif.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
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  3. MXene electrochemical phosphate sensors.Communications engineering · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

JingJing ZhangState Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Chemistry and Biomedicine Innovation Center (ChemBIC), Nanjing University, Nanjing, China; email: jing15209791@nju.edu.cn.
Tian LanGlucoSentient, Inc., Champaign, Illinois, USA.
Yi LuDepartment of Chemistry, University of Texas at Austin, Austin, Texas, USA; email: yi.lu@utexas.edu.
GlucoSentient (United States) · USNanjing University · CNThe University of Texas at Austin · US

Funding

Design and Selection of Novel Metalloenzymes for Biocatalysis, Bioimaging, and Genetic EngineeringR35GM141931 · NIGMS · UNIVERSITY OF TEXAS AT AUSTIN · PI Yi Lu · 2021 to 2026
$3.5M
A rapid and portable test for home monitoring of phenylalanine levels by patients with phenylketonuria using a blood glucose meterR43HD092155 · NICHD · GLUCOSENTIENT, INC. · PI LAN, TIAN · 2017 to 2017
$224k
Developing an Affordable and Pocketable POC Device for Monitoring Lithium and Sodium in Patients with Bipolar DisorderR41MH111337 · NIMH · GLUCOSENTIENT, INC. · PI LAN, TIAN · 2016 to 2016
$211k
NICHD NIH HHS R43 HD092155NIGMS NIH HHS R35 GM141931NIMH NIH HHS R41 MH111337
6 · The paper itself

Abstract

For many years, numerous efforts have been focused on the development of sensitive, selective, and practical sensors for environmental monitoring, food safety, and medical diagnostic applications. However, the transition from innovative research to commercial success is relatively sparse. In this review, we identify four scientific barriers and one technical barrier to developing successful sensors for practical applications, including the lack of general methods to (

Indexed as

Biosensing TechniquesDNA, CatalyticEnvironmental MonitoringPoint-of-Care SystemsDNA, Catalytic(bio)sensordiagnosticfunctional nucleic acidsimagingportable meterSELEX

Identifiers

PMID35216531
PMCPMC9197978
OpenAlexW4214521739

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.