Evidence map›Paper›PMID 35216518›Full record

ArticleJournal of neurotrauma2022

Atrial Natriuretic Peptide and the Epithelial Sodium Channel Contribute to Spinal Cord Injury-Induced Polyuria in Mice.

Xue-Song Sun, Xiao-Long Wang, Ming Bai, Chang Song, Douglas C Eaton, Qiang Yue, Karmarcha K Martin, Hui Cai, Sandra Garraway, Li-Hua Wang and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Xue-Song SunDepartment of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Xiao-Long WangDepartment of Orthopedic Surgery, Cancer Hospital of Harbin Medical University, Harbin, People's Republic of China.
Ming BaiDepartment of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Chang SongDepartment of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
Douglas C EatonRenal Division, Emory University School of Medicine, Atlanta, Georgia, USA.
Qiang YueRenal Division, Emory University School of Medicine, Atlanta, Georgia, USA.
Karmarcha K MartinDepartment of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA.
Hui CaiRenal Division, Emory University School of Medicine, Atlanta, Georgia, USA.
Sandra GarrawayDepartment of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA.
Li-Hua WangDepartment of Neurology, the Second Affiliated Hospital of Harbin Medical University, Harbin, People's Republic of China.
He-Ping MaDepartment of Cell Biology, Emory University School of Medicine, Atlanta, Georgia, USA.
Emory University · USHarbin Medical University · CN

Funding

Role of Ion Channels in Kidney DiseasesR01DK100582 · NIDDK · EMORY UNIVERSITY · PI MA, HE-PING · 2014 to 2017
$1.4M
Regulation of Sodium Transport in Tight EpitheliaR01DK110409 · NIDDK · EMORY UNIVERSITY · PI EATON, DOUGLAS C. · 2018 to 2021
$1.4M
Role of BK Channel in Chronic Kidney DiseaseI01BX000994 · VA · VETERANS HEALTH ADMINISTRATION · PI CAI, HUI · 2012 to 2024
–
BLRD VA I01 BX000994NIDDK NIH HHS R01 DK100582NIDDK NIH HHS R01 DK110409
6 · The paper itself

Abstract

Polyuria is found in patients with spinal cord injury (SCI). However, the underlying cellular and molecular mechanism is unknown. Here, we show that mice had elevated urine for 7 days after T

Indexed as

Atrial Natriuretic FactorSpinal Cord InjuriesAnimalsEpithelial Sodium ChannelsFemaleHumansMaleMicePolyuriaSignal TransductionWaterAtrial Natriuretic FactorEpithelial Sodium ChannelsWateratrial natriuretic peptideENaC intravital imagingpolyuria

Identifiers

PMID35216518
PMCPMC9081061
OpenAlexW4214512247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.