Evidence map›Paper›PMID 35216488›Full record

ReviewInternational journal of molecular sciences2022

The Gut-Skin Microbiota Axis and Its Role in Diabetic Wound Healing-A Review Based on Current Literature.

Bharati Kadamb Patel, Kadamb Haribhai Patel, Ryan Yuki Huang, Chuen Neng Lee, Shabbir M Moochhala

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. The dual role of the microbiome in chronic wound management.Cell communication and signaling : CCS · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Genome-resolved gut metagenomics identifies anFrontiers in immunology · 2026
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. [Research on the pathogenesis and treatment of diabetic foot ulcer wounds].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Bharati Kadamb PatelDepartment of Surgery, National University of Singapore, Singapore 119228, Singapore.
Kadamb Haribhai PatelSchool of Applied Sciences, Temasek Polytechnic, Singapore 529757, Singapore.
Ryan Yuki HuangCanyon Crest Academy, San Diego, CA 92130, USA.
Chuen Neng LeeDepartment of Surgery, National University of Singapore, Singapore 119228, Singapore.
Shabbir M MoochhalaDepartment of Surgery, National University of Singapore, Singapore 119228, Singapore.
National University of Singapore · SGTemasek Polytechnic · SGUniversity of California, San Diego · US

Funding

The Lee Foundation Microbiome Education Fund N-176-000-054-001
6 · The paper itself

Abstract

Diabetic foot ulcers (DFU) are a growing concern worldwide as they pose complications in routine clinical practices such as diagnosis and management. Bacterial interactions on the skin surface are vital to the pathophysiology of DFU and may control delayed wound healing. The microbiota from our skin directly regulates cutaneous health and disease by interacting with the numerous cells involved in the wound healing mechanism. Commensal microbiota, in particular, interact with wound-repairing skin cells to enhance barrier regeneration. The observed microbes in DFU include

Indexed as

AnimalsDiabetes MellitusGastrointestinal MicrobiomeHumansMicrobiotaSkinWound Healingdiabetesdysbiosismicrobiotaprobioticswound healing

Identifiers

PMID35216488
PMCPMC8880500
OpenAlexW4213139208

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.