Evidence map›Paper›PMID 35216418›Full record

ReviewInternational journal of molecular sciences2022

CRISPR/Cas-Mediated Resistance against Viruses in Plants.

Zainul A Khan, Rohit Kumar, Indranil Dasgupta

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Molecular Characterization ofPlants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Study of genetic variability and emerging strains ofPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. A comprehensive review onFrontiers in genetics · 2024
    Review
  15. Article
  16. Role of Plant Virus Movement Proteins in Suppression of Host RNAi Defense.International journal of molecular sciences · 2023
    Review
  17. Exploring C-to-G and A-to-Y Base Editing in Rice by Using New Vector Tools.International journal of molecular sciences · 2022
    Article
  18. Application of CRISPR/CasΦ2 System for Genome Editing in Plants.International journal of molecular sciences · 2022
    Article
  19. Mutation of barleyFrontiers in plant science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zainul A KhanDepartment of Plant Molecular Biology, University of Delhi South Campus, New Delhi 110021, India.
Rohit KumarDepartment of Plant Molecular Biology, University of Delhi South Campus, New Delhi 110021, India.
Indranil DasguptaDepartment of Plant Molecular Biology, University of Delhi South Campus, New Delhi 110021, India.ORCID 0000-0002-1006-4281

Funding

J. C. Bose Fellowship, Science and Engineering Research Board, Government of India SB/S2/JCB-057/2016
6 · The paper itself

Abstract

CRISPR/Cas9 provides a robust and widely adaptable system with enormous potential for genome editing directed towards generating useful products. It has been used extensively to generate resistance against viruses infecting plants with more effective and prolonged efficiency as compared with previous antiviral approaches, thus holding promise to alleviate crop losses. In this review, we have discussed the reports of CRISPR/Cas-based virus resistance strategies against plant viruses. These strategies include approaches targeting single or multiple genes (or non-coding region) in the viral genome and targeting host factors essential for virus propagation. In addition, the utilization of base editing has been discussed to generate transgene-free plants resistant to viruses. This review also compares the efficiencies of these approaches. Finally, we discuss combinatorial approaches, including multiplexing, to increase editing efficiency and bypass the generation of escape mutants.

Indexed as

CRISPR-Cas SystemsGene EditingGenome, PlantGenome, ViralPlants, Genetically ModifiedPlant VirusesCRISPR/Casgenome editingmultiplexingplant virusesvirus resistance

Identifiers

PMID35216418
PMCPMC8879314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.