Evidence map›Paper›PMID 35216318›Full record

ArticleInternational journal of molecular sciences2022

Adipokines as New Biomarkers of Immune Recovery: Apelin Receptor, RBP4 and ZAG Are Related to CD4

Elena Yeregui, Jenifer Masip, Consuelo Viladés, Pere Domingo, Yolanda M Pacheco, Julià Blanco, Josep Mallolas, Verónica Alba, Montserrat Vargas, Graciano García-Pardo and 11 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 7 institutions in 1 country.

Elena YereguiInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Jenifer MasipInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Consuelo ViladésInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Pere DomingoInfectious Diseases Unit, Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, Spain.ORCID 0000-0003-1138-5770
Yolanda M PachecoLaboratory of Immunology, Institute of Biomedicine of Seville, IBiS, 41013 Seville, Spain.
Julià BlancoCIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.ORCID 0000-0002-2225-0217
Josep MallolasCIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Verónica AlbaInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Montserrat VargasInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Graciano García-PardoInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Eugènia NegredoCIBER Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Montserrat OlonaInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.ORCID 0000-0001-5303-9361
Judit Vidal-GonzálezFaculty of Medicine, Universitat de Barcelona (UB), 08007 Barcelona, Spain.
Maria PeraireInfection and Immunity Research Group (INIM), Universitat Rovira i Virgili (URV), 43003 Tarragona, Spain.
Anna MartíInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Laia RevertéInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.ORCID 0000-0003-4690-2387
Fréderic Gómez-BertomeuInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.ORCID 0000-0002-8039-2889
Manuel LealInternal Medicine Service, Hospital Viamed Santa Ángela de la Cruz, 41014 Seville, Spain.
Francesc VidalInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Joaquim PeraireInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.
Anna RullInfection and Immunity Research Group (INIM), Hospital Universitari de Tarragona Joan XXIII (HJ23), 43005 Tarragona, Spain.ORCID 0000-0002-8907-7754
Instituto de Salud Carlos III · ESUniversitat de Vic - Universitat Central de Catalunya · ESHospital de Sant Pau · ESHospital San Juan de la Cruz · ESInstituto de Biomedicina de Sevilla · ESUniversitat de Barcelona · ESUniversitat Rovira i Virgili · ES

Funding

Agency for Administration of University and Research AGAUR (2017SGR948)Centro de Investigación Biomédica en Red CIBERINFEC CB21/13/00020Consejería de Salud del Servicio Andaluz de Salud C-0013-2017Fundación Seimc-Gesida III Premio para Jóvenes Investigadores 2019Institut d'Investigació Sanitària Pere Virgili 2019/IISPV/05Instituto de Salud Carlos III FI20/00118, INT20/00031, CP19/00146Instituto de Salud Carlos III PI16/00503, PI18/01216, PI19/01337 and PI20/00326Red de Investigación en Sida RD12/0017/0005, RD12/0025/0001, RD16/0025/0006
6 · The paper itself

Abstract

A significant proportion of people living with HIV (PLHIV) who successfully achieve virological suppression fail to recover CD4

Indexed as

AdipokinesAdultAntiretroviral Therapy, Highly ActiveApelin ReceptorsBiomarkersCD4 Lymphocyte CountCD4-Positive T-LymphocytesFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedProspective StudiesRetinol-Binding Proteins, PlasmaViral LoadAdipokinesApelin ReceptorsAZGP1 protein, humanBiomarkersRBP4 protein, humanRetinol-Binding Proteins, PlasmaZn-Alpha-2-Glycoproteinadipokinesantiretroviral therapyHIVimmunodiscordant responsepoor immune recovery

Identifiers

PMID35216318
PMCPMC8874604
OpenAlexW4213070696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.