Evidence map›Paper›PMID 35216212›Full record

ReviewInternational journal of molecular sciences2022

Natural Ligand-Mimetic and Nonmimetic Inhibitors of the Ceramide Transport Protein CERT.

Kentaro Hanada, Shota Sakai, Keigo Kumagai

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact, top 100% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 0 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kentaro HanadaDepartment of Quality Assurance, Radiation Safety and Information Management, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan.ORCID 0000-0003-1383-2781
Shota SakaiDepartment of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan.
Keigo KumagaiDepartment of Biochemistry and Cell Biology, National Institute of Infectious Diseases, Shinjuku-ku, Tokyo 162-8640, Japan.
National Institute of Infectious Diseases · JP

Funding

Japan Agency for Medical Research and Development JP20gm0910005j0006Ministry of Education, Culture, Sports, Science and Technology JP17H06417
6 · The paper itself

Abstract

Lipid transfer proteins (LTPs) are recognized as key players in the inter-organelle trafficking of lipids and are rapidly gaining attention as a novel molecular target for medicinal products. In mammalian cells, ceramide is newly synthesized in the endoplasmic reticulum (ER) and converted to sphingomyelin in the

Indexed as

AnimalsBiological TransportCeramidesEndoplasmic ReticulumGolgi ApparatusHumansLigandsProtein Serine-Threonine KinasesCeramidesLigandsProtein Serine-Threonine KinasesCERT1COL4A3BPGolgi apparatusintracellular transport of lipidslipid transfer proteinsmembrane contactoff-target effectssphingolipidsSTART domainstructure-based drug design

Identifiers

PMID35216212
PMCPMC8875512
OpenAlexW3175526400

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.