Evidence map›Paper›PMID 35216190›Full record

ArticleInternational journal of molecular sciences2022

Gel-Based Proteomic Identification of Suprabasin as a Potential New Candidate Biomarker in Endometrial Cancer.

Fulvio Celsi, Lorenzo Monasta, Giorgio Arrigoni, Ilaria Battisti, Danilo Licastro, Michelangelo Aloisio, Giovanni Di Lorenzo, Federico Romano, Giuseppe Ricci, Blendi Ura

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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  13. New Strategies for Endometrial Cancer Detection and Management.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Fulvio CelsiInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0002-9760-8463
Lorenzo MonastaInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0001-7774-548X
Giorgio ArrigoniDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.ORCID 0000-0002-4103-2733
Ilaria BattistiDepartment of Biomedical Sciences, University of Padova, 35131 Padova, Italy.
Danilo LicastroARGO Laboratorio Genomica ed Epigenomica, AREA Science Park, Basovizza, 34149 Trieste, Italy.
Michelangelo AloisioInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.
Giovanni Di LorenzoInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0002-8845-1206
Federico RomanoInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0003-2157-8330
Giuseppe RicciInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.ORCID 0000-0002-8031-1102
Blendi UraInstitute for Maternal and Child Health-IRCCS Burlo Garofolo, 65/1 Via dell'Istria, 34137 Trieste, Italy.
IRCCS Materno Infantile Burlo Garofolo · ITUniversity of Padua · ITAREA Science Park · ITUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cancer (EC) is the most frequent gynaecologic cancer in postmenopausal women. We used 2D-DIGE and mass spectrometry to identify candidate biomarkers in endometrial cancer, analysing the serum protein contents of 10 patients versus 10 control subjects. Using gel-based proteomics, we identified 24 candidate biomarkers, considering only spots with a fold change in volume percentage ≥ 1.5 or intensity change ≤ 0.6, which were significantly different between cases and controls (

Indexed as

AdultAntigens, DifferentiationBiomarkers, TumorDown-RegulationEndometrial NeoplasmsEndometriumFemaleHumansMiddle AgedOncogenesProtein IsoformsProteomeProteomicsTwo-Dimensional Difference Gel ElectrophoresisUp-RegulationAntigens, DifferentiationBiomarkers, TumorProtein IsoformsProteome2D-DIGEendometrial cancermass spectrometryserum proteomeSuprabasinWestern blotting

Identifiers

PMID35216190
PMCPMC8880426
OpenAlexW4213103873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.