Evidence map›Paper›PMID 35216179›Full record

ArticleInternational journal of molecular sciences2022

Genetic Deletion of HLJ1 Does Not Affect Blood Coagulation in Mice.

Man-Chen Hsu, Wei-Jia Luo, Bei-Chia Guo, Chia-Hui Chen, Po-An Hu, Yi-Hsuan Tsai, Kang-Yi Su, Tzong-Shyuan Lee

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In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Man-Chen HsuDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Wei-Jia LuoDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Bei-Chia GuoDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Chia-Hui ChenDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Po-An HuDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Yi-Hsuan TsaiDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.
Kang-Yi SuDepartment of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.ORCID 0000-0002-6538-9526
Tzong-Shyuan LeeDepartment of Physiology, College of Medicine, National Taiwan University, Taipei 10051, Taiwan.ORCID 0000-0002-9593-4062
National Taiwan University · TW

Funding

Ministry of Science and Technology of Taiwan 106-2320-B-002-057-MY3, 106-2320-B-002-056, 106-2811-B-002-146; 108-2811-B-002-542, 108-2320-B-002-032-MY3, and 110-2314-B-002-269
6 · The paper itself

Abstract

HLJ1 (also called DNAJB4) is a member of the DNAJ/Hsp40 family and plays an important role in regulating protein folding and activity. However, there is little information about the role of HLJ1 in the regulation of physiological function. In this study, we investigated the role of HLJ1 in blood coagulation using wild-type C57BL/6 mice and HLJ1-null (HLJ1

Indexed as

AnimalsBiomarkersBlood CoagulationBlood PlateletsGene DeletionHSP40 Heat-Shock ProteinsMaleMegakaryocytesMiceMice, Inbred C57BLPlatelet Membrane Glycoprotein IIbBiomarkersHSP40 Heat-Shock ProteinsPlatelet Membrane Glycoprotein IIbcoagulationDNAJB4HLJ1platelet

Identifiers

PMID35216179
PMCPMC8880458
OpenAlexW4212850525

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.