Evidence map›Paper›PMID 35216162›Full record

ArticleInternational journal of molecular sciences2022

Impaired Functional Connectivity Underlies Fragile X Syndrome.

Lital Gildin, Rossana Rauti, Ofir Vardi, Liron Kuznitsov-Yanovsky, Ben M Maoz, Menahem Segal, Dalit Ben-Yosef

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Transcriptional Dysregulation and Impaired Neuronal Activity inInternational journal of molecular sciences · 2023
    Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lital GildinWolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.ORCID 0000-0003-2735-5568
Rossana RautiDepartment of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.ORCID 0000-0001-8569-0810
Ofir VardiDepartment of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.ORCID 0000-0001-8982-2577
Liron Kuznitsov-YanovskyWolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.
Ben M MaozDepartment of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.ORCID 0000-0002-3823-7682
Menahem SegalDepartment of Brain Sciences, The Weizmann Institute, Rehovot 76100, Israel.ORCID 0000-0001-7592-0408
Dalit Ben-YosefWolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.
Tel Aviv University · ILWeizmann Institute of Science · IL

Funding

Israel Science Foundation 1471/17Tel Aviv University BrainBoostTel Aviv University Leo MintzWeizmann Institute of Science The Azrieli Foundation and the Aufzien Family Center
6 · The paper itself

Abstract

Fragile X syndrome (FXS), the most common form of inherited intellectual disability, is caused by a developmentally regulated silencing of the

Indexed as

Membrane PotentialsTranscriptomeAnimalsBasic Helix-Loop-Helix ProteinsCells, CulturedFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeHuman Embryonic Stem CellsHumansNerve Tissue ProteinsNeural Stem CellsNeurogenesisRatsBasic Helix-Loop-Helix ProteinsFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1Nerve Tissue ProteinsNEUROG1 protein, humandisease modelingelectrophysiologyFragile X syndromehuman embryonic stem cellsMEAneural differentiation

Identifiers

PMID35216162
PMCPMC8878121
OpenAlexW4213165545

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.