Evidence map›Paper›PMID 35216076›Full record

ArticleInternational journal of molecular sciences2022

The G Protein-Coupled Serotonin 1A Receptor Augments Protein Kinase Cε-Mediated Neurogenesis in Neonatal Mouse Hippocampus-PKCε-Mediated Signaling in the Early Hippocampus.

Sreyashi Samaddar, Sudarshana Purkayastha, Souleymane Diallo, Subramanyam J Tantry, Ryan Schroder, Pranavan Chanthrakumar, Michael J Flory, Probal Banerjee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 2 countries.

Sreyashi SamaddarDepartment of Physical Therapy, The College of Staten Island, City University of New York, Staten Island, NY 10314, USA.
Sudarshana PurkayasthaGlobal Health and Wellbeing, Unilever, 18 Nepal Park, Singapore 139407, Singapore.
Souleymane DialloWeiss Memorial Hospital, 4646 Marine Drive, Chicago, IL 60640, USA.
Subramanyam J TantryMedicinal Chemistry at Jubilant Biosys, Bangalore 560022, India.
Ryan SchroderEurofins Lancaster PSS, Merck Sharp and Dohme, Rahway, NJ 07065, USA.
Pranavan ChanthrakumarWarren Alpert Medical School, Brown University, Providence, RI 02903, USA.
Michael J FloryResearch Design and Analysis Service, New York State Institute for Developmental Disabilities, Staten Island, NY 10314, USA.
Probal BanerjeeDepartment of Chemistry, Center for Developmental Neuroscience, The College of Staten Island, City University of New York, Staten Island, NY 10314, USA.ORCID 0000-0001-9429-1010
College of Staten Island · USBrown University · USJubilant Life Sciences (India) · INMerck & Co., Inc., Rahway, NJ, USA (United States) · USNew York State Office for People With Developmental Disabilities · USWeiss Memorial Hospital · US

Funding

The 5-HT1A Receptor and Brain DevelopmentR01MH071376 · NIMH · COLLEGE OF STATEN ISLAND · PI BANERJEE, PROBAL · 2006 to 2008
$711k
National Institute of Health R01MH071376NIMH NIH HHS R01 MH071376
6 · The paper itself

Abstract

The neurotransmitter serotonin (5-HT) plays an important role in mood disorders. It has been demonstrated that 5-HT signaling through 5-HT

Indexed as

8-Hydroxy-2-(di-n-propylamino)tetralinAnimalsAnimals, NewbornApoptosisBromodeoxyuridineDentate GyrusFemaleHippocampusMaleMiceMice, Inbred C57BLNeurogenesisNeuronsProtein Kinase C-epsilonReceptor, Serotonin, 5-HT1AReceptors, G-Protein-Coupled8-Hydroxy-2-(di-n-propylamino)tetralinBromodeoxyuridineProtein Kinase C-epsilonReceptor, Serotonin, 5-HT1AReceptors, G-Protein-CoupledSerotoninSerotonin Receptor Agonists5-HT1A receptordentate gyrusneonatalneurogenesisPKC isozymes

Identifiers

PMID35216076
PMCPMC8878481
OpenAlexW4211095149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.