Evidence map›Paper›PMID 35216060›Full record

ArticleInternational journal of molecular sciences2022

Synergistic Effect of Toceranib and Nanohydroxyapatite as a Drug Delivery Platform-Physicochemical Properties and In Vitro Studies on Mastocytoma Cells.

Paulina Sobierajska, Anna Serwotka-Suszczak, Sara Targonska, Damian Szymanski, Krzysztof Marycz, Rafal J Wiglusz

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. PAD4 Inhibitor-Loaded Magnetic FeInternational journal of nanomedicine · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paulina SobierajskaInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0001-5636-2826
Anna Serwotka-SuszczakDepartment of Experimental Biology, Faculty of Biology and Animal Science, Wroclaw University of Environmental and Life Sciences, C. K. Norwida 27B, 50-375 Wroclaw, Poland.ORCID 0000-0002-4553-0908
Sara TargonskaInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0003-3133-0240
Damian SzymanskiInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0002-3039-7091
Krzysztof MaryczDepartment of Experimental Biology, Faculty of Biology and Animal Science, Wroclaw University of Environmental and Life Sciences, C. K. Norwida 27B, 50-375 Wroclaw, Poland.
Rafal J WigluszInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okolna 2, 50-422 Wroclaw, Poland.ORCID 0000-0001-8458-1532
Polish Academy of Sciences · PLWrocław University of Environmental and Life Sciences · PL

Funding

National Science Center 2019/03/X/NZ5/01138National Science Center UMO-2017/27/N/ST5/02976National Science Center UMO-2018/28/T/ST5/00326
6 · The paper itself

Abstract

A new combination of Toceranib (Toc; 5-[(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-

Indexed as

AnimalsAntineoplastic AgentsCell Line, TumorDog DiseasesDogsDrug CarriersDrug Delivery SystemsDrug SynergismDurapatiteIndolesMastocytomaNanoparticlesProtein Kinase InhibitorsPyrrolesAntineoplastic AgentsDrug CarriersDurapatiteIndolesProtein Kinase InhibitorsPyrrolestoceranib phosphateanticancer drughydroxyapatitemast cell tumournanocarrierssurface propertiestargeted releaseToceranib

Identifiers

PMID35216060
PMCPMC8875076
OpenAlexW4211261914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.