Evidence map›Paper›PMID 35216046›Full record

ArticleInternational journal of molecular sciences2022

Neural Crest Stem Cells in Juvenile Angiofibromas.

Bernhard Schick, Lukas Pillong, Gentiana Wenzel, Silke Wemmert

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bernhard SchickDepartment of Otolaryngology, Saarland University Medical Center, 66421 Homburg, Germany.
Lukas PillongDepartment of Otolaryngology, Saarland University Medical Center, 66421 Homburg, Germany.
Gentiana WenzelDepartment of Otolaryngology, Saarland University Medical Center, 66421 Homburg, Germany.
Silke WemmertDepartment of Otolaryngology, Saarland University Medical Center, 66421 Homburg, Germany.ORCID 0000-0002-7109-5188
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The etiology of juvenile angiofibroma (JA) has been a controversial topic for more than 160 years. Numerous theories have been proposed to explain this rare benign neoplasm arising predominately in adolescent males, focusing mainly on either the vascular or fibrous component. To assess our hypothesis of JA's being a malformation arising from neural crest cells/remnants of the first branchial arch plexus, we performed immunohistochemical analyses of neural crest stem cells (NCSC) and epithelial-mesenchymal transition (EMT) candidates. Immunoexpression of the NCSC marker CD271

Indexed as

AdolescentAdultAngiofibromaChildHumansMaleMiddle AgedNerve Tissue ProteinsNeural CrestNeural Stem CellsYoung AdultNerve Tissue ProteinsCD271epithelial-mesenchymal transitionjuvenile angiofibromaMMP3neural crest stem cell

Identifiers

PMID35216046
PMCPMC8875494
OpenAlexW4210981562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.