Identification of Cryptic Promoter Activity in cDNA Sequences Corresponding to PRRSV 5' Untranslated Region and Transcription Regulatory Sequences.

Jayeshbhai Chaudhari, The Nhu Nguyen, Hiep L X Vu

Open access · goldAbstract read

In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it

0cells of the map it votes in

4citing papers in PubMed

1.6field-weighted citation impact, top 20% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

When RNA goes off script: ensuring transcript fidelity in transgene expression.The EMBO journal · 2026
Review
The commercial PRRSV attenuated vaccine can be a potentially effective live trivalent vaccine vector.Applied microbiology and biotechnology · 2025
Article
ZNF283, a Krüppel-associated box zinc finger protein, inhibits RNA synthesis of porcine reproductive and respiratory syndrome virus by interacting with Nsp9 and Nsp10.Veterinary research · 2024
Article
A Single Amino Acid Substitution in Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 2 Significantly Impairs Its Infectivity in Macrophages.Viruses · 2022
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jayeshbhai ChaudhariNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0002-1864-562X

The Nhu NguyenNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0003-0079-7358

Hiep L X VuNebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68583, USA.ORCID 0000-0001-8084-4358

University of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the role of PRRSV nonstructural proteins (nsps) in viral RNA replication and transcription, we generated a cDNA clone of PRRSV strain NCV1 carrying the nanoluciferase (

Indexed as

Promoter Regions, Genetic5' Untranslated RegionsAnimalsCell LineDNA, ComplementaryGenes, ReporterPorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusRNA, ViralSwineVirus Replication5' Untranslated RegionsDNA, ComplementaryRNA, Viral5′ untranslated region (5′ UTR)eukaryotic promoternanoluciferase (nluc)porcine reproductive and respiratory syndrome virus (PRRSV)transcription regulatory sequence (TRS)

Identifiers

PMID35215993

DOI10.3390/v14020400

PMCPMC8874549

OpenAlexW4213009685

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.