Evidence map›Paper›PMID 35215920›Full record

ArticleViruses2022

New Emergence of the Novel Pestivirus Linda Virus in a Pig Farm in Carinthia, Austria.

Alexandra Kiesler, Lukas Schwarz, Christiane Riedel, Sandra Högler, René Brunthaler, Katharina Dimmel, Angelika Auer, Marianne Zaruba, Marlene Mötz, Kerstin Seitz and 3 more

Abstract read
In one paragraph

Article in Viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. GFP-Tagged EViruses · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexandra KieslerDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.ORCID 0000-0001-8840-033X
Lukas SchwarzUniversity Clinic for Swine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.ORCID 0000-0002-4716-4913
Christiane RiedelDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.ORCID 0000-0002-4349-996X
Sandra HöglerDepartment for Pathobiology, Institute of Pathology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
René BrunthalerDepartment for Pathobiology, Institute of Pathology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Katharina DimmelDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Angelika AuerDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Marianne ZarubaDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Marlene MötzDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Kerstin SeitzDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.ORCID 0000-0003-2852-5047
Andrea LadinigUniversity Clinic for Swine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.
Benjamin LampFaculty of Veterinary Medicine, Institute of Virology, Justus-Liebig-University Giessen, Schubertstrasse 81, 35392 Giessen, Germany.
Till RümenapfDepartment for Pathobiology, Institute of Virology, University of Veterinary Medicine, Veterinaerplatz 1, 1210 Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Linda virus (LindaV) was first identified in a pig farm in Styria, Austria in 2015 and associated with congenital tremor (CT) type A-II in newborn piglets. Since then, only one more LindaV affected farm was retrospectively discovered 10 km away from the initially affected farm. Here, we report the recent outbreak of a novel LindaV strain in a farrow-to-finish farm in the federal state Carinthia, Austria. No connection between this farm and the previously affected farms could be discovered. The outbreak was characterized by severe CT cases in several litters and high preweaning mortality. A herd visit two months after the onset of clinical symptoms followed by a diagnostic workup revealed the presence of several viremic six-week-old nursery pigs. These animals shed large amounts of virus via feces and saliva, implying an important epidemiological role for within- and between-herd virus transmission. The novel LindaV strain was isolated and genetically characterized. The findings underline a low prevalence of LindaV in the Austrian pig population and highlight the threat when introduced into a pig herd. Furthermore, the results urge the need to better understand the routes of persistence and transmission of this enigmatic pestivirus in the pig population.

Indexed as

AnimalsAustriaCommunicable Diseases, EmergingDisease OutbreaksFarmsFecesPestivirusPestivirus InfectionsPhylogenyRetrospective StudiesSwineSwine Diseasesatypical porcine pestivirusAustriaBungowannah viruscongenital tremoremerging diseaseFlaviviridaeLinda virusnovel Linda virus strainpestivirusviruses

Identifiers

PMID35215920
PMCPMC8874435

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.